Protein Alignment toy and rx3

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571302.1
• Gene: rx3 / 30474
• ZFINID: ZDB-GENE-990415-238
• Length: 292
• Species: Danio rerio
• Alignment Length: 351
• Identity: 97/351 - (27%)
• Similarity: 154/351 - (43%)
• Gaps: 94/351 - (26%)

  Fly   130 RLLSEQVCNSDNIPSVSSINRVLRNLASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYP-----S 189
            ||:..|..:.::..|.|:  |::|:..||....:       .|.:..|.|:|.....:|     :
Zfish     2 RLVGSQYKDMEDRLSPSA--RLVRSPGSQTRIHS-------IESILGFKGETLFHPAFPYGSGKT 57

  Fly   190 NTTTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDED 254
            ...|.||          ||...|.: ..|.|.:..:..|.::       ..:||.   ..|.||:
Zfish    58 GKDTEHL----------SPKKDSNK-HFDGVCRSTVMVSPDL-------PDADGG---KLSDDEN 101

  Fly   255 SQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAK 319
            .      |:|.:||||:|:..|:..||:.||::|||||::||.||.|:.|||.|:||||.|||||
Zfish   102 P------KKKHRRNRTTFTTFQLHELERAFEKSHYPDVYSREELALKVNLPEVRVQVWFQNRRAK 160

  Fly   320 WRREEKM-----RTQRRSADTVDGSGRTSTANN-PSGTTASSSVATSNN---STPGIVN------ 369
            |||:||:     :.|..|..::..||..|..:. |.....:..::||::   |.|..:.
Zfish   161 WRRQEKLEVSSIKLQESSMLSIPRSGPLSLGSGLPLEPWLTGPISTSSSPLQSLPSFITPQQAVP 225

  Fly   370 SAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPP-----------LQPAAPRLPLN 423
            ::....:..||:.:::|||                |..:..||           ||.|.||
Zfish   226 ASYTPPQFLSSSTLNHSLP----------------HIGAVCPPYQCSGFMDKFSLQEADPR---- 270

  Fly   424 SGFNTMYSSIPQPIATMAENYNSSLG 449
               ||..:|    :...|:.:..|:|
Zfish   271 ---NTSIAS----LRMKAKEHIQSIG 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	6/22 (27%)
		COG5576	<253..368	CDD:227863	51/123 (41%)
		Homeodomain	267..322	CDD:459649	34/54 (63%)
rx3	NP_571302.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/26 (27%)
		Octapeptide motif	32..39		1/13 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..72		6/28 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..107		8/37 (22%)
		Homeodomain	107..163	CDD:459649	34/55 (62%)
		OAR	268..284	CDD:461067	6/26 (23%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	272..285		3/16 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	278..282		0/3 (0%)