Protein Alignment toy and rx1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571300.2
• Gene: rx1 / 30472
• ZFINID: ZDB-GENE-990415-236
• Length: 330
• Species: Danio rerio
• Alignment Length: 237
• Identity: 81/237 - (34%)
• Similarity: 114/237 - (48%)
• Gaps: 54/237 - (22%)

  Fly   198 LPPAASVVTSPA-----NLSGQADRD--DVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDS 255
            |||.......|.     ..|.:.|.|  |::|     ::|          ||..|..::.|::.
Zfish    85 LPPLRDGSEQPTFHDADMFSNKCDGDLGDLRK-----AIE----------SDSKSPDSADGEQP- 133

  Fly   256 QMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKW 320
                  |:|.:||||:|:..|:..||:.||::|||||::||.||.|:.|||.|:||||.||||||
Zfish   134 ------KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKW 192

  Fly   321 RREEKMRTQRRSADTVD-GSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAIN--VAERTSSAL 382
            ||:||:     .|.|:. ......:.|.||   ...:|...|||.|      ::  :....|||.
Zfish   193 RRQEKI-----DASTMKLHDSPMLSFNRPS---MHPTVGPMNNSLP------LDPWLPSPLSSAT 243

  Fly   383 VSNSLPEASNGPTVLGGEANTTHTSSESPP------LQPAAP 418
            ..:|:| ...||| .|.:......|..|||      :||.||
Zfish   244 PVHSIP-GFMGPT-QGLQTGYPGHSFLSPPQPMAQSMQPMAP 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	50/115 (43%)
		Homeodomain	267..322	CDD:459649	34/54 (63%)
rx1	NP_571300.2	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..104		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..142		9/40 (23%)
		Homeodomain	138..194	CDD:459649	34/55 (62%)
		OAR	302..318	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319
		Nuclear localization signal. /evidence=ECO:0000255	312..316