DRSC/TRiP Functional Genomics Resources

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Protein Alignment toy and Otp

DIOPT Version :10

Sequence 1:NP_001368990.1 Gene:toy / 43833 FlyBaseID:FBgn0019650 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_001093993.1 Gene:Otp / 294640 RGDID:727945 Length:325 Species:Rattus norvegicus


Alignment Length:385 Identity:93/385 - (24%)
Similarity:142/385 - (36%) Gaps:115/385 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 GQTGGWAWYPSNTTTAHLTLPPAASVVT---SPANLSGQADRDDVQKRELQFSVEVSHTNSHDST 240
            |..|..|  |::......||.|...:.|   :||:|:..|...|.|                 ..
  Rat    40 GHPGDLA--PNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQ-----------------PG 85

  Fly   241 SDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLP 305
            ..|....:.:|.:..|      :|.:|:||.|:..|::.||:.|.:|||||:|.||.||.:|||.
  Rat    86 PQGGPNPSQAGQQQGQ------QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144

  Fly   306 EARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNS 370
            |:|:||||.||||||::.:|.....|:..|:     ..|...|...:|:::.|            
  Rat   145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTL-----LPTPGLPQFPSAAAAAA------------ 192

  Fly   371 AINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQ 435
                               |:.|.::....||.|..::.:   .|...:|||             
  Rat   193 -------------------AAMGDSLCSFHANDTRWAAAA---MPGVSQLPL------------- 222

  Fly   436 PIATMAENYNSSLGSMTPSCLQQRDAYPYMFHD-PLSLGSPYVSAHHRNTACNPSAA----H-QQ 494
                             |..|.::.|....... .|:.|.|..|....|:....:.|    | .|
  Rat   223 -----------------PPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQ 270

  Fly   495 PPQHGVYTNSSPMPSSNTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQXSSIFGSPLDH 554
            |...|:...|.|.||:.:|            |.|..|....|:.|.....:|:....|:|
  Rat   271 PAFPGMVPASLPGPSNVSG------------SPQLCSSPDSSDVWRGTSIASLRRKALEH 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toyNP_001368990.1 PAX 29..153 CDD:128645
COG5576 <253..368 CDD:227863 42/114 (37%)
Homeodomain 267..322 CDD:459649 33/54 (61%)
OtpNP_001093993.1 Homeodomain 106..156 CDD:459649 28/49 (57%)
OAR 303..320 CDD:461067 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

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