DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and GSC2

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_005306.1	Gene:	GSC2 / 2928	HGNCID:	4613	Length:	205	Species:	Homo sapiens

Alignment Length:	82	Identity:	38/82 - (46%)
Similarity:	52/82 - (63%)	Gaps:	0/82 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 KRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKM 326
            :|:.:|:||.||.||:.:||..|.:..||||..|||||.:|.|.|.|::|||.|||||||.:::.
Human   123 QRRTRRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKRA 187

  Fly   327 RTQRRSADTVDGSGRTS 343
            ....|....|..|.:.|
Human   188 SASARLLPGVKKSPKGS 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	38/82 (46%)
		Homeobox	269..322	CDD:395001	31/52 (60%)
GSC2	NP_005306.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	33..58
		Homeobox	129..182	CDD:278475	30/52 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..205		4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940