Protein Alignment toy and Duxbl1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_899245.1
• Gene: Duxbl1 / 278672
• MGIID: 1916048
• Length: 350
• Species: Mus musculus
• Alignment Length: 293
• Identity: 70/293 - (23%)
• Similarity: 112/293 - (38%)
• Gaps: 65/293 - (22%)

  Fly   248 NSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVW 312
            :....|..|.:.|:| :.:|:||.|:..|.|.|.:.||:..:|.:..||:||.:.|:||:||.:|
Mouse    78 SEESQEQEQDKPRVK-EARRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIW 141

  Fly   313 FSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANN---PSGTTASSSVATSNNSTPGIVNSAINV 374
            |.||||: ..:....||:.........|.|.....   ||.|..||:......|.|...|..:::
Mouse   142 FQNRRAR-HPDPGQNTQKTPHPPQSSQGPTQKTVGKLAPSKTLTSSASVILPLSPPHTPNGPLDL 205

  Fly   375 AERTSSALVSNSLPEASN----------------GPTVLGGE-------------ANTTHTSSES 410
            ::.....|...:|.::|.                .||...||             .|..|...||
Mouse   206 SKGRQKQLPGTTLLQSSQVVQQRSDDQNPNKGHLSPTTTPGEQGFHSQPPLQLLTQNRGHNPRES 270

  Fly   411 PPLQPAAPRL------PLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCL-------QQRDAY 462
            ..|  |.|||      |   ..|..:..:.|..::..::::...|||....:       ::.:.:
Mouse   271 GGL--AVPRLEDCTQVP---AVNQHFRKLDQNDSSFLQHWDEWFGSMLAEWMPDKEYWSEKAELH 330

  Fly   463 PYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQP 495
            |:             ....|..|.....|||.|
Mouse   331 PW-------------QVQLRQLASVSPQAHQTP 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	40/117 (34%)
		Homeodomain	267..322	CDD:459649	25/54 (46%)
Duxbl1	NP_899245.1	homeodomain	15..71	CDD:238039
		Homeodomain	95..149	CDD:459649	25/54 (46%)