Protein Alignment toy and Otx1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_037241.2
• Gene: Otx1 / 25646
• RGDID: 3237
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 84/264 - (31%)
• Similarity: 126/264 - (47%)
• Gaps: 38/264 - (14%)

  Fly   263 RKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREE--- 324
            ||.:|.||:|:..|:|.||..|.:|.|||:|.||.:|.||.|||:|:||||.|||||.|:::
  Rat    36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSG 100

  Fly   325 ---KMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNS 386
               |.|..::.:..|    |.|:.:..||.....:|::|.:|:....:::.|.|...::.|..|.
  Rat   101 NGTKSRPVKKKSSPV----RESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNP 161

  Fly   387 LPEAS--NGPTVLGGEANTTHTSSESPPLQPAAPRLP----LNSGFNTMYSSIPQPIATMAENYN 445
            :..||  :.||.    ::....:|.||...||:..:|    ..|..:.|..|:....||.|.:|.
  Rat   162 VAAASSLSTPTA----SSIWSPASISPGSAPASVSVPEPLGAPSNASCMQRSVAAGAATAAASYP 222

  Fly   446 SSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPM-PS 509
            .|.|        |..:|...:..|   .|.|......::...|..:|..|.|      .||| ||
  Rat   223 MSYG--------QGGSYGQGYPAP---SSSYFGGVDCSSYLAPMHSHHHPHQ------LSPMAPS 270

  Fly   510 SNTG 513
            |..|
  Rat   271 SMAG 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	45/110 (41%)
		Homeodomain	267..322	CDD:459649	32/54 (59%)
Otx1	NP_037241.2	Homeodomain	39..95	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..144		12/55 (22%)
		TF_Otx	178..274	CDD:427350	30/112 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..306		10/24 (42%)