DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and Gm4981

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001030041.1	Gene:	Gm4981 / 245263	MGIID:	3645498	Length:	291	Species:	Mus musculus

Alignment Length:	276	Identity:	68/276 - (24%)
Similarity:	100/276 - (36%)	Gaps:	75/276 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 LKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEK 325
            ::...:|..|..:..|...|.:.|||...|....||.||.:.||||..|..|..|:||  ||..:
Mouse     1 MRSSSRRPHTGLTLSQRRILAQAFERNPRPGCATREELALETGLPEDMIHTWLKNKRA--RRHRR 63

  Fly   326 MRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEA 390
            .|...:..|.:                 :|.|  |..:..|.|.....||:       .:|||:.
Mouse    64 GRPTAQDQDLL-----------------ASQV--SGGAPAGPVGRGHEVAQ-------ESSLPQE 102

  Fly   391 SNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSC 455
            ..|.|.:    :||.||     ..|:..|       .:..|.:.||.....:...:..|::.|..
Mouse   103 EAGSTGM----DTTSTS-----YSPSFCR-------ESQLSQVSQPRGAGQKEVPTQAGNVGPLE 151

  Fly   456 L---------QQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMPSSN 511
            |         |.::..|    |||.|||            :|.|...:..|..:   .|...::|
Mouse   152 LLLDELQDEVQVKEHVP----DPLDLGS------------DPGAREPEGSQDSL---QSLDEAAN 197

  Fly   512 TGVISAGVSVPVQIST 527
            :|   ...|||...||
Mouse   198 SG---WHTSVPSISST 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	29/106 (27%)
		Homeobox	269..322	CDD:395001	20/52 (38%)
Gm4981	NP_001030041.1	homeodomain	6..56	CDD:238039	18/49 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900