Protein Alignment toy and Ldb3

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_036048.3
• Gene: Ldb3 / 24131
• MGIID: 1344412
• Length: 723
• Species: Mus musculus
• Alignment Length: 461
• Identity: 88/461 - (19%)
• Similarity: 151/461 - (32%)
• Gaps: 161/461 - (34%)

  Fly    89 GSIKPRAI-GGSKPRVATTPVVQKIADYKRECPSIFAWEIRDR-----LLSEQVCNSD-NIPSVS 146
            ||:.|:.: |.|:||....|:....|:..||...::...:|.:     ||...:...| .:.|.|
Mouse   176 GSVSPKVLPGPSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGAGLLGGSLPVKDLAVDSAS 240

  Fly   147 SINRVLRNLASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANL 211
            .:.:.:....|:.|.:|.:                  ||...||
Mouse   241 PVYQAVIKTQSKPEDEADE------------------WARRSSN--------------------- 266

  Fly   212 SGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQ 276
                    :|.|..:...:::.|           |:....||::         |:|:.|...
Mouse   267 --------LQSRSFRILAQMTGT-----------EYMQDPDEEA---------LRRSSTPIE--- 300

  Fly   277 IDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGR 341
                       |.|                                   :.|.:.::..:..|.:
Mouse   301 -----------HAP-----------------------------------VCTSQATSPLLPASAQ 319

  Fly   342 TSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEAS-NGPTVLGGEANTTH 405
            :..|.:|  ..||.::||:     ...::|...|...:::.|.|..|:|| ..|......|.:.|
Mouse   320 SPAAASP--IAASPTLATA-----AATHAAAASAAGPAASPVENPRPQASAYSPAAAASPAPSAH 377

  Fly   406 TSSESPPLQPA-APRLPLNSGFNTMYSSIPQPIATMAENYNSSLG---SMTPSCLQQRDAY---- 462
            ||....|..|| .||:...:   ::..|:.||:.  |.:|:.|.|   |.||.......||
Mouse   378 TSYSEGPAAPAPKPRVVTTA---SIRPSVYQPVP--ASSYSPSPGANYSPTPYTPSPAPAYTPSP 437

  Fly   463 -PYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMPS-SNTGVISAGVSVPVQI 525
             |.....|....||           :|:.|:...|.    .|.:|.|| :.:|..|...|.|..:
Mouse   438 APTYTPSPAPTYSP-----------SPAPAYTPSPA----PNYTPTPSAAYSGGPSESASRPPWV 487

  Fly   526 STQNVS 531
            :..:.|
Mouse   488 TDDSFS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	17/70 (24%)
		COG5576	<253..368	CDD:227863	14/114 (12%)
		Homeobox	269..322	CDD:395001	3/52 (6%)
Ldb3	NP_036048.3	PDZ_signaling	5..81	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..134
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..193		7/16 (44%)
		DUF4749	191..293	CDD:374237	23/168 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..423		42/223 (19%)
		PHA03247	<378..528	CDD:223021	35/136 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..525		16/73 (22%)
		LIM1_ZASP_Cypher	547..598	CDD:188838
		LIM2_Enigma_like	606..657	CDD:188748
		LIM3_ZASP_Cypher	665..719	CDD:188844

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030