Protein Alignment toy and Prop1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_032962.1
• Gene: Prop1 / 19127
• MGIID: 109330
• Length: 223
• Species: Mus musculus
• Alignment Length: 260
• Identity: 80/260 - (30%)
• Similarity: 104/260 - (40%)
• Gaps: 97/260 - (37%)

  Fly   239 STSDGNSE--HNSSGDEDSQMRLRLKR----KLQRNRTSFSNEQIDSLEKEFERTHYPDVFARER 297
            ||.|.:||  ...||.|..:.:|..:|    ..:|:||:|:..|::.||..|.|..|||::|||.
Mouse    34 STVDRSSEAYRRLSGTELGRPKLCPQRGRPHSRRRHRTTFNPAQLEQLESAFGRNQYPDIWAREG 98

  Fly   298 LADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNN 362
            ||...||.||||||||.|||||.|::|:
Mouse    99 LAQDTGLSEARIQVWFQNRRAKQRKQER------------------------------------- 126

  Fly   363 STPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFN 427
                   |.:......|:|..|..|||:|..|...|           :||  |.||..|
Mouse   127 -------SLLQPIAHLSTATFSGFLPESSAYPYTYG-----------TPP--PPAPCFP------ 165

  Fly   428 TMYS-SIPQPIATMAENYNSSLGSMTPSCLQQRDAYPY----------------MFHDPLSLGSP 475
            ..|| |:|...:|.|     || ::.|   |..|.||.                ||  ||||.:|
Mouse   166 HPYSHSLPSQPSTAA-----SL-ALPP---QPEDWYPTLHPAPTGHLPCPPPPPMF--PLSLETP 219

  Fly   476  475
            Mouse   220  219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	37/118 (31%)
		Homeodomain	267..322	CDD:459649	32/54 (59%)
Prop1	NP_032962.1	Homeodomain	67..123	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..223		20/63 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		10/34 (29%)