DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and pax-2

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_500513.1	Gene:	pax-2 / 187062	WormBaseID:	WBGene00003938	Length:	351	Species:	Caenorhabditis elegans

Alignment Length:	276	Identity:	110/276 - (39%)
Similarity:	148/276 - (53%)	Gaps:	69/276 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 STAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGS 90
            |...|:|:||||||:||||||||:.|.:|||::..|.|||||||.|:||:|||||||||||.|||
Worm    88 SDGSHTGVNQLGGVFVNGRPLPDTIRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGS 152

  Fly    91 IKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRN- 154
            ::|..||||||:|||..||:.||.|||..|::||||||.:|:.:|:|..:|:||||||||::||
Worm   153 VRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNK 217

  Fly   155 ---------------------LASQKE-------QQAQQQNESVYEKLRMFNGQTGGWAWYPSNT 191
                                 ..||.:       ||..||:.|| ::|:.|.        ..|..
Worm   218 SFMAQLATPTSVTPSVARPSSATSQNQRSPPRGVQQHMQQSTSV-QQLQQFQ--------LTSAA 273

  Fly   192 TTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGN----SEHNSS-- 250
            |...|...||.::..:..:::|                 :..|..|.|..|..    |.|::.
Worm   274 TVNSLISRPAFAIPGTTHSING-----------------LLGTFPHSSLLDDKFTNLSTHSADMS 321

  Fly   251 --------GDEDSQMR 258
                    |:.|..||
Worm   322 LVYPTGLVGEHDWAMR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	81/123 (66%)
		COG5576	<253..368	CDD:227863	3/6 (50%)
		Homeobox	269..322	CDD:395001
pax-2	NP_500513.1	PAX	91..215	CDD:128645	81/123 (66%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010