Protein Alignment toy and Pax7

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_006538692.1
• Gene: Pax7 / 18509
• MGIID: 97491
• Length: 505
• Species: Mus musculus
• Alignment Length: 592
• Identity: 194/592 - (32%)
• Similarity: 267/592 - (45%)
• Gaps: 158/592 - (26%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
Mouse    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    94 RAIGGSKPR-VATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPS--VSSINRVLRNL 155
            .|||||||| |||..|.:||.:||||.|.:|:||||||||.:..|:...:||  ||||:||||..
Mouse    99 GAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIK 163

  Fly   156 ASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDV 220
            ..:||                                                       |.::.
Mouse   164 FGKKE-------------------------------------------------------DDEEG 173

  Fly   221 QKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFE 285
            .|:|.....:..|:........||.....| |.:|:..|.||||.:|:||:|:.||::.|||.||
Mouse   174 DKKEEDGEKKAKHSIDGILGDKGNRLDEGS-DVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 237

  Fly   286 RTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSG 350
            ||||||::.||.||.:..|.|||:|||||||||:||::
Mouse   238 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ--------------------------- 275

  Fly   351 TTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVL---GGEANTTHTSSESPP 412
             ..::.:|..|:..||      .........|....||:::...|.:   ||  :|.|.....||
Mouse   276 -AGANQLAAFNHLLPG------GFPPTGMPTLPPYQLPDSTYPTTTISQDGG--STVHRPQPLPP 331

  Fly   413 -------LQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPL 470
                   |..||.....:|.:...:|         ..:|:.|.  |.|..       |....:|:
Mouse   332 STMHQGGLAAAAAAADTSSAYGARHS---------FSSYSDSF--MNPGA-------PSNHMNPV 378

  Fly   471 SLG-SPYVSAHHRNTACNPSAAHQQP-------PQHGVYTNSSPMPSS---NTGVISAGVSVPVQ 524
            |.| ||.|    .:...||||...||       |.||...::|.:.:|   ....|..|.|:|..
Mouse   379 SNGLSPQV----MSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTS 439

  Fly   525 IS---------TQNVSDLTGSNYWPRLQXSSIFG-SPLDHLSKATAAAIIAAQAAEKSHKHRKEH 579
            .|         ..:|..:.|..|       |.:| :.:|:|:|..:   ::.|...|..:|....
Mouse   440 QSYCPPTYSTTGYSVDPVAGYQY-------SQYGQTAVDYLAKNVS---LSTQRRMKLGEHSAVL 494

  Fly   580 SIVSIHT 586
            .::.:.|
Mouse   495 GLLPVET 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	82/126 (65%)
		COG5576	<253..368	CDD:227863	46/114 (40%)
		Homeodomain	267..322	CDD:459649	35/54 (65%)
Pax7	XP_006538692.1	PAX	34..161	CDD:128645	82/126 (65%)
		Homeodomain	218..274	CDD:459649	35/55 (64%)
		Pax7	347..385	CDD:403540	11/55 (20%)