DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and Pax1

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_006498974.1	Gene:	Pax1 / 18503	MGIID:	97485	Length:	534	Species:	Mus musculus

Alignment Length:	205	Identity:	99/205 - (48%)
Similarity:	126/205 - (61%)	Gaps:	33/205 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 INQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKPRAIG 97
            :||||||:|||||||::.|.:|||||..|.|||||||.|:||:|||||||.||.|||||.|.|||
Mouse   181 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIG 245

  Fly    98 GSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRN----LASQ 158
            ||||||.|..||:.|.|||:..|.|||||||||||::.||:..|:||||||:|:|||    ||..
Mouse   246 GSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQP 310

  Fly   159 KEQQAQQQ--------NESVYE------------KLRMFNGQTGGWAWYPSNTTTAHLTLPPAAS 203
            ...:|.:|        ...:|:            |:....|..|         :..|:::|.:..
Mouse   311 GPYEASKQPPPQPALPYNHIYQYPYPSPVSPTGTKMGTHPGVPG---------SAGHVSIPRSWP 366

  Fly   204 VVTSPANLSG 213
            ...|.:|:.|
Mouse   367 SAHSVSNILG 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	83/119 (70%)
		COG5576	<253..368	CDD:227863
		Homeobox	269..322	CDD:395001
Pax1	XP_006498974.1	PAX	177..304	CDD:238076	86/122 (70%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910