Protein Alignment toy and vab-3

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001024570.1
• Gene: vab-3 / 181251
• WormBaseID: WBGene00006870
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 235/541 - (43%)
• Similarity: 306/541 - (56%)
• Gaps: 117/541 - (21%)

  Fly    26 STAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGS 90
            |.|||:|:||||||:||||||||:|||:||:|||.|.|||||||:||||||||||||.||||:|:
 Worm     2 SDAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGT 66

  Fly    91 IKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNL 155
            |:|||||||||||||:.||:||.||||:.||||||||||:||::.:||::.||||||||||||||
 Worm    67 IRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNL 131

  Fly   156 ASQKEQQAQQQNESVYEKLRMFNGQTGGWAWY-----PSNTTTAHLTLPPAASVVTSPANLSGQA 215
            |::|||...|  ..:|:::|:.:......:||     |.|.........||..:   .....|:.
 Worm   132 AAKKEQVTMQ--TELYDRIRIVDNFPYNSSWYGQWPIPMNGAVGLNPFVPAPLI---EPKTEGEF 191

  Fly   216 DRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSL 280
            ::|:.||..                        :..::|:..|:|||||||||||||:..||:||
 Worm   192 EKDEDQKPP------------------------TEPEDDAAARMRLKRKLQRNRTSFTQVQIESL 232

  Fly   281 EKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTA 345
            |||||||||||||||||||.||.|||||||||||||||||||||||| .:||:.|:|     |:.
 Worm   233 EKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMR-NKRSSGTMD-----SSL 291

  Fly   346 NNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSES 410
            :|.:.|....||..||.:.|      |.....|.:...||:   ::|.||     .|....:|:
 Worm   292 SNGTPTPTPGSVTGSNMTNP------IGSPASTPNRFPSNN---SANLPT-----TNFVPQTSQ- 341

  Fly   411 PPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLG---SMTPSCLQQRDAYP----YMFHD 468
                              ||:.:.||   ..:.|:..:.   ||.|        ||    :..|.
 Worm   342 ------------------MYAGLSQP---AMDPYSFGIANGFSMAP--------YPQVTDFQPHH 377

  Fly   469 PLSLGSPYVSAHHRNTACNPSAAHQQPPQ-HGVYTNSSPMPSS--NTGVISAGVSVPVQISTQNV 530
            .....|||...:.|           .|.. ||...:.||..::  :...:|:|:|:||.....::
 Worm   378 MFQGRSPYDFPYPR-----------MPTNGHGFQQSMSPATTAVGDIPTLSSGMSLPVSAVLNSI 431

  Fly   531 ------------SDLTGSNYW 539
                        ||||..:||
 Worm   432 DPSLTHSQMHELSDLTQEHYW 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	96/123 (78%)
		COG5576	<253..368	CDD:227863	76/114 (67%)
		Homeodomain	267..322	CDD:459649	48/54 (89%)
vab-3	NP_001024570.1	PAX	5..129	CDD:128645	96/123 (78%)
		Homeodomain	219..274	CDD:459649	48/54 (89%)