DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and Lhx8

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_034843.2	Gene:	Lhx8 / 16875	MGIID:	1096343	Length:	367	Species:	Mus musculus

Alignment Length:	150	Identity:	37/150 - (24%)
Similarity:	62/150 - (41%)	Gaps:	31/150 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 QRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQR 330
            :|.||||:.:|:..::.:|.:.:.||....::||::.||....|||||.|.||:.::.
Mouse   247 KRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKH------- 304

  Fly   331 RSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPT 395
                         .:.|.|.:...::|.:|..|.|       .:.|...||.|    |:.....|
Mouse   305 -------------VSPNHSSSAPVTAVPSSRLSPP-------MLEEMAYSAYV----PQDGTMLT 345

  Fly   396 VLGGEANTTHTSSESPPLQP 415
            .|....:......:|.|..|
Mouse   346 ALHSYMDAHQQLLDSSPCYP 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	27/101 (27%)
		Homeobox	269..322	CDD:395001	20/52 (38%)
Lhx8	NP_034843.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..79
		LIM1_Lhx7_Lhx8	95..150	CDD:188767
		LIM2_Lhx7_Lhx8	157..211	CDD:188769
		Homeobox	250..302	CDD:278475	20/51 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940