Protein Alignment toy and sv

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_061505297.1
• Gene: sv / 1272219
• VectorBaseID: AGAMI1_004208
• Length: 561
• Species: Anopheles gambiae
• Alignment Length: 566
• Identity: 169/566 - (29%)
• Similarity: 239/566 - (42%)
• Gaps: 184/566 - (32%)

  Fly    30 HSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKPR 94
            |.|:||||||:||||||||..||:||||||:|.|||||||.|:||:|||||||.|||||||.|..
Mosquito    19 HGGVNQLGGVFVNGRPLPDLVRQRIVELAHNGIRPCDISRQLRVSHGCVSKILSRYYETGSFKAG 83

  Fly    95 AIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLASQK 159
            .||||||:|||.|||:.||.||.:.|::|||||||:||::.:|..||:||||||||::||.|::|
Mosquito    84 VIGGSKPKVATPPVVEAIAAYKLQNPTMFAWEIRDKLLADGICVHDNVPSVSSINRIVRNKAAEK 148

  Fly   160 -------------------------EQQAQQQN-----------------------ESVYEKLRM 176
                                     :||:|||.                       |:|..:...
Mosquito   149 AKYSSQRSDNSSMDSPRILSRNNQQQQQSQQQQQQQECLNQQMQADQESMKSPQQVENVASQSYS 213

  Fly   177 FNGQTG--------------------GWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQ 221
            .||..|                    |.....:||....||  |..|:.....::.....||...
Mosquito   214 INGLLGLSQKSLSGSSSKRRRIKEDPGKHLLTTNTILRPLT--PRFSLADMKGSMLSCIKRDKET 276

  Fly   222 KRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNR------------TSFSN 274
            |       ::|.:..|||...|      .|.:..|.:.:.:::.|:::            :|.:.
Mosquito   277 K-------DMSESMLHDSIGKG------GGQDQQQQQQQQQQQQQQDKGHDLFVGGVDFVSSLAM 328

  Fly   275 EQIDSLEKEFERTHYPDVFARERLADKIGLP-EARIQVWF----SNRRAKWRR-EEKMRT----- 328
            .|.|....:.::..:..:....|.......| .:|....|    .::..|:.| :|.|.|
Mosquito   329 AQDDGNNPDNQQAGFSSMRTGPRPGTMSSSPIRSRENALFLLAGGDKAHKYHRTDEPMPTGVIIE 393

  Fly   329 ---------QRRSA----------------DTVDGSG---RTSTANN----PSGTTASSSVATSN 361
                     |::.|                :.|.|||   .:|:|||    ||..|.|....:..
Mosquito   394 DDSSARKHQQQQQAHQANDVKTTYDKILAGELVPGSGVKRASSSANNAATEPSALTQSIEFLSDM 458

  Fly   362 NS----------TPGIVNSAINVAERTSSALVSNSLPE----ASNGPTVLGGEANTTHTSSESPP 412
            |:          .....:.|.:.|:...:|:..|  |.    :||....|   .||...::.:|.
Mosquito   459 NNNIAQNQHQGFAAAAYDGAYSAADAADTAVQLN--PHLAACSSNYSAFL---QNTDQFAAANPE 518

  Fly   413 L--------QPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGS 450
            |        |.|||      |:.|.             |||||..:
Mosquito   519 LIFPTAAYTQYAAP------GYGTF-------------NYNSSFAN 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	87/122 (71%)
		COG5576	<253..368	CDD:227863	29/179 (16%)
		Homeodomain	267..322	CDD:459649	8/71 (11%)
sv	XP_061505297.1	None