Protein Alignment toy and Pax3

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 191/604 - (31%)
• Similarity: 268/604 - (44%)
• Gaps: 181/604 - (29%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
  Rat    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    94 RAIGGSKPRVATTP-VVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLAS 157
            .|||||||:..||| |.:||.:||||.|.:|:|||||:||.:.||:.:.:||||||:|:||
  Rat    99 GAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILR---- 159

  Fly   158 QKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQK 222
                       |.:.|                                       |:.:..|:::
  Rat   160 -----------SKFGK---------------------------------------GEEEEADLER 174

  Fly   223 RELQFSVEVSHTNSHDSTSDGNS--EHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFE 285
            :|.:.|.:.:..:.....|:..|  :.:...|.||:..|.||||.:|:||:|:.||::.||:.||
  Rat   175 KEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239

  Fly   286 RTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANN--P 348
            ||||||::.||.||.:..|.|||:|||||||||:||::.             |:.:....|:  |
  Rat   240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA-------------GANQLMAFNHLIP 291

  Fly   349 SG--TTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESP 411
            .|  .||..::.|               .:.:.::....|:|:|.:.|      ::|.|.....|
  Rat   292 GGFPPTAMPTLPT---------------YQLSETSYQPTSIPQAVSDP------SSTVHRPQPLP 335

  Fly   412 PLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPY 476
            |              :|::.|      |:..|.:||.....||......:|...|..|....:|
  Rat   336 P--------------STVHQS------TIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNP- 379

  Fly   477 VSAHHRNTACNPSAAHQQPPQ-HGVYTNSSPMPSSNTGVISAGVSVPVQISTQ-NVSDLTGSNYW 539
                     .||:..:...|| .|:.||..              .||.|..|. .:|.|||.
  Rat   380 ---------MNPAIGNGLSPQVMGLLTNHG--------------GVPHQPQTDYALSPLTGG--- 418

  Fly   540 PRLQXSSIFGSPLDHLSKATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTTCCS 604
                           |...|..:...:|        |.||          .||..||......|.
  Rat   419 ---------------LEPTTTVSASCSQ--------RLEH----------MKNVDSLPTSQPYCP 450

  Fly   605 SRYLNMTFGAGKDVDVVIG 623
            ..|..    .|..:|.|.|
  Rat   451 PTYST----TGYSMDPVTG 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	80/124 (65%)
		COG5576	<253..368	CDD:227863	49/118 (42%)
		Homeobox	269..322	CDD:395001	33/52 (63%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	80/124 (65%)
		MFAP1	164..>286	CDD:336570	51/173 (29%)
		Homeobox	222..276	CDD:333795	33/53 (62%)
		Pax7	347..391	CDD:289156	11/53 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810