DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and mxtx1

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_571635.2	Gene:	mxtx1 / 100149566	ZFINID:	ZDB-GENE-000710-7	Length:	309	Species:	Danio rerio

Alignment Length:	350	Identity:	85/350 - (24%)
Similarity:	129/350 - (36%)	Gaps:	92/350 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 DSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKI 302
            |||.|..::.:.||   :..|...:||    |||||.|.::.|...||...||.:..||.|:...
Zfish     4 DSTIDATAKTSGSG---AVSRSASRRK----RTSFSKEHVELLRATFETDPYPGISLRESLSQTT 61

  Fly   303 GLPEARIQVWFSNRRAK-----------WRRE---------EKMRTQRRSADTVDGSGRTSTANN 347
            ||||:||||||.||||:           |:.:         ..|:..|::.::   ||.|
Zfish    62 GLPESRIQVWFQNRRARTLKCKGGKKPLWQTDLPAYNNMQTSPMQIHRKNNES---SGAT----- 118

  Fly   348 PSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPP 412
              ||..|...|..:.....:...|:...:..||..:|:.....:  |:.....|..:| .|.||.
Zfish   119 --GTLCSPPPAYPDRIKEEMEKDAVCGCDTPSSMSISDDSGYCT--PSYHQSRAIQSH-MSPSPL 178

  Fly   413 LQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYV 477
            |.|.                     ..|..|:....|..:|..               |:.|||
Zfish   179 LSPE---------------------HQMPPNWGVRYGRRSPMS---------------SMWSPY- 206

  Fly   478 SAHHRNTACNPSAAHQQPPQHGVYTNSSPMPSSNTGVISAGVSVPVQISTQNVSDLTGSNYWPRL 542
              |....||||...:....:|......:|: :.::|...||:.....:...:|         ||.
Zfish   207 --HLEAYACNPGFFYSHSEKHNTLQPLTPV-TPDSGCWEAGLDRTSPVDNPDV---------PRT 259

  Fly   543 Q---XSSIFGSPLDHLSKATAAAII 564
            :    |.:...||..|...:...|:
Zfish   260 EGQLESGVHHGPLPELPTLSLQEIL 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	41/134 (31%)
		Homeobox	269..322	CDD:395001	29/63 (46%)
mxtx1	NP_571635.2	HOX	24..78	CDD:197696	29/57 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810