Protein Alignment toy and shox2

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001093694.1
• Gene: shox2 / 100101703
• XenbaseID: XB-GENE-480993
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 379
• Identity: 90/379 - (23%)
• Similarity: 127/379 - (33%)
• Gaps: 150/379 - (39%)

  Fly   224 ELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRL----RLKRKLQRNRTSFSNEQIDSLEKEF 284
            ||..|||....:.....::.:.|.....:|..|..|    :.|.|.:|:||:|:.||::.||:.|
 Frog    75 ELDLSVERIRESGSPKLTEVSPEIKERKEELKQQALEEEGQTKIKQRRSRTNFTLEQLNELERLF 139

  Fly   285 ERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPS 349
            :.|||||.|.||.|:.::||.|||:||||.|||||.|::|
 Frog   140 DETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQE------------------------- 179

  Fly   350 GTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQ 414
                                               |.|.:.     ||.|..:.......:|.:.
 Frog   180 -----------------------------------NQLHKG-----VLIGAGSQFEACRVAPYVN 204

  Fly   415 PAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSA 479
            ..|.|:|..   ...:.::|            ||.....:.||              |.|....|
 Frog   205 VGALRMPFQ---QDSHCNVP------------SLSFQVQAQLQ--------------LDSAVAHA 240

  Fly   480 HHRNTACNPSAAHQQPPQHGVYTNSSPMPSSNTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQX 544
            ||.        .|.....|..|. ..|.|.
 Frog   241 HHH--------LHPHLTAHAPYM-MFPAPP----------------------------------- 261

  Fly   545 SSIFGSPLDHLS--KATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSL 596
               ||.||..|:  .||||:::||.||.|:..  |..||..:. .|.||:..:|
 Frog   262 ---FGLPLATLAAETATAASVVAAAAAAKTSS--KNSSIADLR-LKAKKHAAAL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	39/118 (33%)
		Homeobox	269..322	CDD:395001	31/52 (60%)
shox2	NP_001093694.1	Homeobox	123..177	CDD:365835	31/53 (58%)
		OAR	292..307	CDD:367680	5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940