Protein Alignment PlexA and plxna3

DIOPT Version :10

• Sequence 1: NP_524637.2
• Gene: PlexA / 43832
• FlyBaseID: FBgn0025741
• Length: 1945
• Species: Drosophila melanogaster
• Sequence 2: NP_001006866.1
• Gene: plxna3 / 448633
• XenbaseID: XB-GENE-856557
• Length: 429
• Species: Xenopus tropicalis
• Alignment Length: 408
• Identity: 131/408 - (32%)
• Similarity: 195/408 - (47%)
• Gaps: 79/408 - (19%)

  Fly    63 STITNVAAFDTKLNHLLVDTITGRVFVGGVNRLYQLSPDLELSETVKTGPQNDSVECSILDCPLN 127
            |.....|..||.|.||.|...||.|::|.|||:::||.:|....:..|||..|:..|    .|..
 Frog    21 SVFPTFAVSDTSLTHLAVHKHTGDVYLGAVNRIFKLSENLTELRSHLTGPIADNSSC----YPPP 81

  Fly   128 AVR------SPTDNYNKVLLIDRATSRLIACGSLFQGTCTVRNLQNVSII-------EHEV---- 175
            :||      |||||.|::||||....|::||||::||.|....|.::..:       ||.:
 Frog    82 SVRVCTHKLSPTDNVNRLLLIDYTGKRVVACGSVWQGICQFLRLDDLFKLGEPHHRKEHYLSGAR 146

  Fly   176 -PDA----VVANDANSSTVAFIAPGPPQHPVTNVMYVGVTYTNNSPYRSEIPAVASRSL----EK 231
             ||:    :|..|...|.                :::|.:....|.|   .|.::||.|    |.
 Frog   147 EPDSMAGVIVDQDVEQSK----------------LFIGTSIDGKSEY---FPTLSSRRLVQDEES 192

  Fly   232 TKMFQI------ASSAVTTGTRTFINSYARETYFVNYVYGFSSERFSYFLTTQLKHSH----HSS 286
            .:||::      .||.:...:.|.   ....::.:.|||||.|:.|.||||.||....    .:.
 Frog   193 AEMFRLVYQDEFVSSQIKVPSDTL---SLHPSFDIYYVYGFVSKIFVYFLTLQLDTQQTLLDATG 254

  Fly   287 PKEYITKLVRICQEDSNYYSYTEIPVECISDAQGGTKFNLVQAGFLGKPSSDLAQSLGISIQDDV 351
            .|.:.:|:||:|..|..:|||.|.|:.|..|   |.::.|:|:.:|.:|...|||:|||...::|
 Frog   255 EKFFTSKIVRMCSGDLEFYSYVEFPIGCTKD---GVEYRLIQSAYLSRPGRKLAQALGIPEDEEV 316

  Fly   352 LFAVFSKGEGN--TPTNNSALCIYSLKSIRRKFMQNIKSCFNGSGMRGLDFISPSMPCVLTKLQT 414
            ||.|||:|:.|  .|...|.||:::|..|.......|:||::|.|       ..|:|.:|.|
 Frog   317 LFTVFSQGQKNRSNPPRESVLCLFTLSQINLHIKMRIQSCYHGEG-------KLSLPWLLNK--- 371

  Fly   415 IGEDFCGLDVNSPLGGET 432
              |.||...|:..:|..|
 Frog   372 --ELFCISTVSGCIGAFT 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PlexA	NP_524637.2	Sema_plexin_like	75..520	CDD:200497	127/396 (32%)
		PSI	522..574	CDD:396154
		TIG_plexin	580..670	CDD:465588
		PSI	671..>702	CDD:396154
		TIG_2	738..829	CDD:465619
		PSI	830..883	CDD:396154
		IPT_plexin_repeat1	885..977	CDD:238585
		IPT_plexin_repeat2	978..1063	CDD:238584
		IPT	1078..1177	CDD:472823
		TIG	<1196..>1246	CDD:460355
		Plexin_cytopl	1353..1911	CDD:462434
plxna3	NP_001006866.1	Sema	22..>378	CDD:472829	127/396 (32%)