Protein Alignment PlexA and LOC108179158

DIOPT Version :10

• Sequence 1: NP_524637.2
• Gene: PlexA / 43832
• FlyBaseID: FBgn0025741
• Length: 1945
• Species: Drosophila melanogaster
• Sequence 2: NP_001429833.1
• Gene: LOC108179158 / 108179158
• -ID: -
• Length: 826
• Species: Danio rerio
• Alignment Length: 1118
• Identity: 232/1118 - (20%)
• Similarity: 376/1118 - (33%)
• Gaps: 376/1118 - (33%)

  Fly    67 NVAAFDTKLNHLLVDTITGRVFVGGVNRLYQLSPDLELSETVKTGPQNDSVECSILDCPLNAVRS 131
            :|..||..:...:|.  .|::||...|||||:..|  |||..|....|:|..      |:|.:..
Zfish    19 DVVDFDGDIKDFVVG--NGKLFVLTENRLYQMRHD--LSEEKKKNDINNSTH------PVNILVP 73

  Fly   132 PTDNYNKVLLIDRATSRLIACGSLFQGTCTVRNLQNVSIIEHEVPDAVVANDANSSTVAFIAPGP 196
            ..||           ..||.||:...|.|.|.::.::....:...:..:.......:|||||.
Zfish    74 FDDN-----------GTLITCGTYEDGYCEVLDINDIKNSIYYESNLFIGPKETEKSVAFIAG-- 125

  Fly   197 PQHPVTNVMYVGVTYTNNSPY----------RSEIPAVASRSLEKTKMFQIASSAVTTGTRTFIN 251
                           |::|.|          .|:.|.|...:..:|:...|.|.| ..|:...|.
Zfish   126 ---------------TSSSRYLLIGKKLDQSTSQSPVVRLWNTLQTQFGGILSYA-EQGSEPAIQ 174

  Fly   252 SYARETYFVNYVYGFSSERFSYFLTTQ---------LKHSHHSSPKEYITKLVRICQEDSNYYSY 307
            |.|.:..||:.....||.....||.|:         |..:...|.|..|.|            |.
Zfish   175 STANDVKFVDGFQRASSSDLYLFLNTKTDSERKVHVLWMNSSKSTKSEIFK------------SL 227

  Fly   308 TEIPVECISDAQGGTKFNLVQAGFLGKPSSDLAQSLGISIQDDVLFA-VFSKGEGNTPTNNSALC 371
            ....::|.||                |....|..|..|..:..|::| |||..:...| .|:||.
Zfish   228 QSAVIKCCSD----------------KARPVLVSSAVIPSEKAVIWAGVFSAQDQQDP-ENTALA 275

  Fly   372 IYSLKSIRRKFMQNIKSCFNGSGMRGLDFISPSMPCVLTKLQTIGEDFCGLDVNSPLGGETPITS 436
            :|::..|:.:                           :.:....||..||.:..|.|   .|::
Zfish   276 LYNISRIQGR---------------------------VKEFCAAGERMCGSESGSNL---QPLS- 309

  Fly   437 VPVAMFNTKLTSVAATSTSGYTVVFVGTSDGFLKKVVIESSSIANEYAS------FAVDLGSEIN 495
              |.:.::.::||||.....:.|:|:|||||.|.|:|::.:     |..      :..|....:.
Zfish   310 --VIIKSSSMSSVAAVRNGSWIVLFMGTSDGQLIKLVLDEN-----YTPGCPTVLYKSDDERAVL 367

  Fly   496 RDMQFDNQNL-YIYVMSKTKVSKVKVFDCSDYKTCGDCLGARDPYCGWCSLENKCSPRSNCQDDA 559
            ..:.||..:. :||:....|:.:|.|..|:.|.|..||..|.||.||||....:||.:..|.:.:
Zfish   368 PRLHFDPVDFKHIYIALGKKIRRVSVVHCAKYNTLMDCRSALDPLCGWCVNTLRCSTQDKCSNSS 432

  Fly   560 NDPLYWVSYKTGKCTTITSVVPHQLQRTTARTLELIIDHLPQLKENLICAFTTEDKALFTNATKK 624
                 |||            :|                     |.:|
Zfish   433 -----WVS------------IP---------------------KNSL------------------ 441

  Fly   625 RNGVNCTTPRTDMLP-QIEQ-GKHHFTAKLSVRTRNGPDLVSTDFTFFDC-STHSSCTRCVSSE- 685
                     :|::|. |:.| ....||..|::      .|.||....|.| .:|.:...|..|:
Zfish   442 ---------QTELLSFQVAQKSSTEFTLHLAL------SLESTGNPAFSCVFSHGNVNLCDESDL 491

  Fly   686 ---FPCDWCVEAHRCTHDTAENCR-NDILVTGVSRIGPSYRSGPGFCPTINATGDGSEVLVAGGT 746
               ||        :|      :|| :|.||                                  .
Zfish   492 TAVFP--------KC------SCRFSDQLV----------------------------------N 508

  Fly   747 SKSIKVKVHIIGQFIVQTRFVCQFNIEGRVTSLNAQLLGDTIYCDSMEFQYTSRSPNLTATFAVI 811
            ::.:||...:..:             :.::|.:  .:|.:   |.|:    |..|||::.|
Zfish   509 TEDLKVSATVTVE-------------DQKITKM--LILSN---CSSI----TDNSPNVSYT---- 547

  Fly   812 WGGSKPLDNPHNIHVVIYRCREMADSCGICLALSEKYNCGWCSSTNTCEVEEQCNKNKEGKTDWL 876
                                     .|..|::    ..|.|.||:..|....:....       |
Zfish   548 -------------------------QCVQCIS----SGCHWSSSSQRCYWSHESGLQ-------L 576

  Fly   877 NRSEICPN-------PEIHTFQPKTGPWEGGTNITIRGINLGKNYNDIYSGVRIAG-INCMPFPQ 933
            |..:.|.:       |||.:.:|....:.|..|:.::|.||     |..:.:||.| ::|:....
Zfish   577 NIQDACKDVLSGYKEPEILSLEPYKVSFHGKNNVLLKGRNL-----DSVTKIRIRGDLDCVAKES 636

  Fly   934 FYIDTKQIVCTVDSPGEQMYRNGKIVVQIGD--YRGESKEDYEFVDPKILDFNPKFGPTSGGTEI 996
            ...|........:.|..:.....|:.|...|  ..|.|...|. ..||.....|:....|||.:|
Zfish   637 PVFDGSSDTLRFNIPPSETKGTVKLCVVTPDNLCHGNSNIIYS-SQPKCTGVQPRSSWRSGGRKI 700

  Fly   997 HITGKHLNAGSRIQASINDHLPCKILSTDSSQAICRTSASPGIIEGRLKMSFDNGPREFNDYNFK 1061
            |:.|.::.....:....::.:.....:|::.:....:....|  .|:|.:|.:.|....:
Zfish   701 HVQGTNMEYVESVNVCHSNKVVETKYNTNAEEMWIHSPRYDG--SGQLSLSLNVGNSTVD----- 758

  Fly  1062 YVLDPTVEHVSSGPSGQIKVPKGIPAGGIRISVTGTQFTSIQNPNIYVVY----NGEMYASPCRV 1122
                 .|.::|..|.     ||            .|||::.|..:..:||    ..|:..|...|
Zfish   759 -----CVHYISYHPD-----PK------------FTQFSTFQVADDLLVYIQKKTDELNLSMSEV 801

  Fly  1123 -----QSDTEMEC 1130
                 |.|.|.||
Zfish   802 NVTGQQGDREYEC 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PlexA	NP_524637.2	Sema_plexin_like	75..520	CDD:200497	107/471 (23%)
		PSI	522..574	CDD:396154	18/51 (35%)
		TIG_plexin	580..670	CDD:465588	13/91 (14%)
		PSI	671..>702	CDD:396154	7/35 (20%)
		TIG_2	738..829	CDD:465619	11/90 (12%)
		PSI	830..883	CDD:396154	9/52 (17%)
		IPT_plexin_repeat1	885..977	CDD:238585	22/94 (23%)
		IPT_plexin_repeat2	978..1063	CDD:238584	15/84 (18%)
		IPT	1078..1177	CDD:472823	16/62 (26%)
		TIG	<1196..>1246	CDD:460355
		Plexin_cytopl	1353..1911	CDD:462434
LOC108179158	NP_001429833.1	None