DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PlexA and LOC108179158

DIOPT Version :9

Sequence 1:	NP_524637.2	Gene:	PlexA / 43832	FlyBaseID:	FBgn0025741	Length:	1945	Species:	Drosophila melanogaster
Sequence 2:	XP_017210788.1	Gene:	LOC108179158 / 108179158	-ID:	-	Length:	321	Species:	Danio rerio

Alignment Length:	351	Identity:	84/351 - (23%)
Similarity:	126/351 - (35%)	Gaps:	91/351 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 NVAAFDTKLNHLLVDTITGRVFVGGVNRLYQLSPDLELSETVKTGPQNDSVECSILDCPLNAVRS 131
            :|..||..:...:|.  .|::||...|||||:..|  |||..|....|:|..      |:|.:..
Zfish    19 DVVDFDGDIKDFVVG--NGKLFVLTENRLYQMRHD--LSEEKKKNDINNSTH------PVNILVP 73

  Fly   132 PTDNYNKVLLIDRATSRLIACGSLFQGTCTVRNLQNVSIIEHEVPDAVVANDANSSTVAFIAPGP 196
            ..||           ..||.||:...|.|.|.::.::....:...:..:.......:|||||.
Zfish    74 FDDN-----------GTLITCGTYEDGYCEVLDINDIKNSIYYESNLFIGPKETEKSVAFIAG-- 125

  Fly   197 PQHPVTNVMYVGVTYTNNSPY----------RSEIPAVASRSLEKTKMFQIASSAVTTGTRTFIN 251
                           |::|.|          .|:.|.|...:..:|:...|.|.| ..|:...|.
Zfish   126 ---------------TSSSRYLLIGKKLDQSTSQSPVVRLWNTLQTQFGGILSYA-EQGSEPAIQ 174

  Fly   252 SYARETYFVNYVYGFSSERFSYFLTTQ---------LKHSHHSSPKEYITKLVRICQEDSNYYSY 307
            |.|.:..||:.....||.....||.|:         |..:...|.|..|.|            |.
Zfish   175 STANDVKFVDGFQRASSSDLYLFLNTKTDSERKVHVLWMNSSKSTKSEIFK------------SL 227

  Fly   308 TEIPVECISDAQGGTKFNLVQAGFLGKPSSDLAQSLGISIQDDVLFA-VFSKGEGNTPTNNSALC 371
            ....::|.||                |....|..|..|..:..|::| |||..:...| .|:||.
Zfish   228 QSAVIKCCSD----------------KARPVLVSSAVIPSEKAVIWAGVFSAQDQQDP-ENTALA 275

  Fly   372 IYSLKSIRRKFMQNIKSCFNGSGMRG 397
            :|::..|:.:..:   .|..|..|.|
Zfish   276 LYNISRIQGRVKE---FCAAGERMCG 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PlexA	NP_524637.2	Sema_plexin_like	75..520	CDD:200497	81/343 (24%)
		PSI	522..574	CDD:279745
		PSI	671..>699	CDD:279745
		PSI	830..883	CDD:279745
		IPT_plexin_repeat1	885..977	CDD:238585
		IPT_plexin_repeat2	978..1063	CDD:238584
		IPT	1078..1177	CDD:301692
		IPT_PCSR	1196..>1255	CDD:238337
		Plexin_cytopl	1353..1916	CDD:285529
LOC108179158	XP_017210788.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D90434at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010