DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbeta and atp5f1b

DIOPT Version :9

Sequence 1:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001001256.1	Gene:	atp5f1b / 407968	XenbaseID:	XB-GENE-943110	Length:	525	Species:	Xenopus tropicalis

Alignment Length:	514	Identity:	444/514 - (86%)
Similarity:	463/514 - (90%)	Gaps:	9/514 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALRAASKADKNLLPFLGQ--LSTAPFSARSHAAKAAKAAAAAN-----GKIVAVIGAVVDVQFDD 60
            ||||...|...:.  |||  |..:|.:..|....||:.:|||.     |:||||||||||||||:
Frog    12 ALRALKPASNPVQ--LGQNLLRCSPAALHSRRDYAAQTSAAAKPGTAVGRIVAVIGAVVDVQFDE 74

  Fly    61 NLPPILNALEVDNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDTGYPIRIPVGAETLG 125
            .||||||||||..|..||||||||||||||||||||||||||||||||||.|.|||||||.||||
Frog    75 GLPPILNALEVQGRDTRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDAGTPIRIPVGPETLG 139

  Fly   126 RIINVIGEPIDERGPIDTDKTAAIHAEAPEFVQMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGG 190
            ||:|||||||||||||.|.:.|||||||||||:||||||||||||||||||||||||||||||||
Frog   140 RIMNVIGEPIDERGPITTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGG 204

  Fly   191 AGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYNEMIEGGVISLKDKTSKVALVYGQM 255
            ||||||||||||||||||||||||||||||||||||||||:||||.|||:|||.|||||||||||
Frog   205 AGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDTTSKVALVYGQM 269

  Fly   256 NEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAT 320
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Frog   270 NEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAT 334

  Fly   321 DMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLD 385
            |||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Frog   335 DMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLD 399

  Fly   386 STSRIMDPNIIGQEHYNVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQP 450
            ||||||||||:|.|||.||||||||||||||||||||||||||||||||||||||||||||||||
Frog   400 STSRIMDPNIVGLEHYEVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQP 464

  Fly   451 FQVAEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVAFYMVGPIEEVVEKADRLAKE 509
            ||||||||||.||||||:.|||||..||.|.||:|||.||||||||||.|.||::||:|
Frog   465 FQVAEVFTGHLGKLVPLKDTIKGFKQILHGGYDNLPEQAFYMVGPIEEAVTKAEKLAEE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	425/462 (92%)
		ATP-synt_ab_N	46..112	CDD:280947	59/65 (91%)
		F1-ATPase_beta	114..393	CDD:238553	266/278 (96%)
		ATP-synt_ab_C	401..508	CDD:278722	92/106 (87%)
atp5f1b	NP_001001256.1	PRK09280	55..521	CDD:236447	425/465 (91%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	420	1.000	Domainoid score	I634
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1273
Inparanoid	1	1.050	832	1.000	Inparanoid score	I446
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278669at33208
OrthoFinder	1	1.000	-	-		FOG0001822
OrthoInspector	1	1.000	-	-		oto102268
Panther	1	1.100	-	-	LDO	PTHR15184
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1349
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.160