DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATPsynbeta and Uty

DIOPT Version :9

Sequence 1:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_017174175.1	Gene:	Uty / 22290	MGIID:	894810	Length:	1236	Species:	Mus musculus

Alignment Length:	334	Identity:	57/334 - (17%)
Similarity:	117/334 - (35%)	Gaps:	100/334 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 TREGNDLYNEMIEGGVISLKDK-TSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLL 286
            |:|..|..::.:.... |.||: ||.:.     :|....:.....::.:.::.....:.....|:
Mouse   555 TKESKDSRSKSLTSKT-SRKDRDTSNIC-----VNAKKHSNHIYQISSVPISSLNNKESVSPDLI 613

  Fly   287 FIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGSMQERITTTKKGSITSVQ-AIYVPADDL 350
            .:||        .::|.|:|.....|.:      |:|:..:         :.:|. ||:...|:|
Mouse   614 IVDN--------PQLSVLVGETIDNVDH------DIGTCDK---------VNNVHLAIHKKPDNL 655

  Fly   351 TDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPN-----IIGQEHYNV------- 403
            :..:|::..    :|..||..:.|        .....:..:.|:     |.|:.|.|:
Mouse   656 SASSPSSAI----STETLSLKLTE--------QTHIVTSFISPHSGLHTINGEGHENLESSASVN 708

  Fly   404 --ARGVQKILQD-----YKSLQDIIAI---LGMDELSE----------------------EDKL- 435
              .|...:|:..     |.|..:::..   ||.:.||.                      ::||
Mouse   709 VGLRPRSQIIPSMSVSIYSSSTEVLKACRSLGKNGLSNGHILLDICPPPRPPTSPYPPLPKEKLN 773

  Fly   436 ----TVARARK-------IQRFLSQPFQVAEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVA 489
                ::....|       :.:|...|.....|..|.||.| .|:..:.....::..:.:|:.||.
Mouse   774 PPTPSIYLENKRDAFFPPLHQFCINPKNPVTVIRGLAGAL-KLDLGLFSTKTLVEANNEHIVEVR 837

  Fly   490 FYMVGPIEE 498
            ..::.|.:|
Mouse   838 TQLLQPADE 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	57/334 (17%)
		ATP-synt_ab_N	46..112	CDD:280947
		F1-ATPase_beta	114..393	CDD:238553	28/171 (16%)
		ATP-synt_ab_C	401..508	CDD:278722	25/149 (17%)
Uty	XP_017174175.1	TPR repeat	88..116	CDD:276809
		TPR repeat	121..178	CDD:276809
		TPR	130..397	CDD:223533
		TPR repeat	183..213	CDD:276809
		TPR repeat	224..252	CDD:276809
		TPR repeat	262..297	CDD:276809
		TPR repeat	304..331	CDD:276809
		TPR repeat	336..366	CDD:276809
		TPR repeat	371..399	CDD:276809
		JmjC	935..999	CDD:214721
		JmjC	969..1077	CDD:334913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900