DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATPsynbeta and rbr-2

DIOPT Version :9

Sequence 1:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_502032.2	Gene:	rbr-2 / 177985	WormBaseID:	WBGene00004319	Length:	1477	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	60/302 - (19%)
Similarity:	107/302 - (35%)	Gaps:	110/302 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 ERTREGNDLYNEMIE-----GGVISLKDKTSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQE 280
            |:..|..|.|:..:|     ..||.:||.:.               |||...|.....:..:|
Worm   908 EKIIEEGDEYDIKLEEIDELRKVIQMKDWSD---------------RARKVTTWKATPDMEKD-- 955

  Fly   281 GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATD--MGSMQERITTTKKGSITSVQAI 343
                   ||..::...|.|::.:|:...|.    .||..|.  :..:|:.:.
Worm   956 -------IDFEYKLRYASSDILSLIRDSPR----NPTDGTSKLVFELQQMLR------------- 996

  Fly   344 YVPADDLTDPAPATTFAHLDATT--VLSRAIAELGIYPAVDPLDST-SRIMDPNIIGQEHYNVAR 405
                               ||.|  |::....|   .||:|.|.|. ..:.:.:...:::.|:.|
Worm   997 -------------------DANTLEVIANNFCE---NPALDQLQSIWQSLRETDWFYEKYINMVR 1039

  Fly   406 ----GVQKILQDYKSLQDIIAILGMDELSEED-----------KLTVARARKIQRFLSQPFQVAE 455
                .|.||    ||:.|    ..:..|||.|           ::|:::|.:|    |:.|:.::
Worm  1040 YEIIHVAKI----KSMID----AAIPVLSEFDLKTQLQKIVNVEITLSKAAEI----SKAFETSK 1092

  Fly   456 VFTG---HAGKLVPLEQTIKGFSAILA------GDYDHLPEV 488
            ...|   |.| ::.:..|:..|:..:|      ..|.:|.|:
Worm  1093 CLNGSEEHLG-ILDMISTMNAFTQRIAILFKPNNAYHNLFEI 1133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	60/302 (20%)
		ATP-synt_ab_N	46..112	CDD:280947
		F1-ATPase_beta	114..393	CDD:238553	34/181 (19%)
		ATP-synt_ab_C	401..508	CDD:278722	26/112 (23%)
rbr-2	NP_502032.2	JmjN	55..96	CDD:128818
		BRIGHT	122..214	CDD:128777
		PHD_SF	321..368	CDD:304600
		JmjC	501..617	CDD:202224
		zf-C5HC2	709..761	CDD:280996
		PLU-1	788..1130	CDD:285609	58/297 (20%)
		PHD	1208..1254	CDD:214584
		PHD3_KDM5A_like	1413..1463	CDD:277083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900