DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbeta and atp-2

DIOPT Version :9

Sequence 1:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_498111.2	Gene:	atp-2 / 175716	WormBaseID:	WBGene00000229	Length:	538	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	426/511 - (83%)
Similarity:	459/511 - (89%)	Gaps:	4/511 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALRAAS-KADKNLLPFLGQLSTAPFSARSHAAK--AAKAAAA-ANGKIVAVIGAVVDVQFDDNLP 63
            ||.||| :...|.:.....:.|...:.::.||.  :|||.|| |:|:||||||||||||||:|||
Worm    25 ALPAASIRLSSNNVESKKGIHTGVATQQAAAATKVSAKATAANASGRIVAVIGAVVDVQFDENLP 89

  Fly    64 PILNALEVDNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDTGYPIRIPVGAETLGRII 128
            ||||.|||..|||||:|||:||||:|.||.|||||||||||||.|.|||.||:||||.||||||:
Worm    90 PILNGLEVVGRSPRLILEVSQHLGDNVVRCIAMDGTEGLVRGQPVADTGDPIKIPVGPETLGRIM 154

  Fly   129 NVIGEPIDERGPIDTDKTAAIHAEAPEFVQMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGV 193
            |||||||||||||.:...|||||||||||:|||||||||||||||||||||||||||||||||||
Worm   155 NVIGEPIDERGPIASKNFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGV 219

  Fly   194 GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYNEMIEGGVISLKDKTSKVALVYGQMNEP 258
            |||||||||||||||||||||||||||||||||||||:||||||||.||.|.|||:|||||||||
Worm   220 GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVIDLKGKNSKVSLVYGQMNEP 284

  Fly   259 PGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMG 323
            |||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Worm   285 PGARARVCLTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMG 349

  Fly   324 SMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTS 388
            |||||||||||||||||||||||||||||||||||||||||||||||.||||.||||||||||||
Worm   350 SMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELAIYPAVDPLDSTS 414

  Fly   389 RIMDPNIIGQEHYNVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFQV 453
            ||||||::||.||::||||||||||||||||||||||||||||||||||:|||||||||||||||
Worm   415 RIMDPNVVGQNHYDIARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQV 479

  Fly   454 AEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVAFYMVGPIEEVVEKADRLAKE 509
            |||||||.||.|.||:||:||:.||.|:.||||||||||.|.|::|.:||:.|||:
Worm   480 AEVFTGHQGKFVSLEETIRGFTMILKGELDHLPEVAFYMQGGIDDVFKKAEELAKQ 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	408/462 (88%)
		ATP-synt_ab_N	46..112	CDD:280947	54/65 (83%)
		F1-ATPase_beta	114..393	CDD:238553	261/278 (94%)
		ATP-synt_ab_C	401..508	CDD:278722	85/106 (80%)
atp-2	NP_498111.2	PRK09280	67..533	CDD:236447	409/465 (88%)
		ATP-synt_ab_N	72..138	CDD:280947	54/65 (83%)
		F1-ATPase_beta	140..419	CDD:238553	261/278 (94%)
		ATP-synt_ab_C	427..535	CDD:278722	86/107 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164626
Domainoid	1	1.000	414	1.000	Domainoid score	I337
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1273
Inparanoid	1	1.050	813	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62497
OrthoDB	1	1.010	-	-		D278669at33208
OrthoFinder	1	1.000	-	-		FOG0001822
OrthoInspector	1	1.000	-	-		oto17463
orthoMCL	1	0.900	-	-		OOG6_100608
Panther	1	1.100	-	-	LDO	PTHR15184
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R118
SonicParanoid	1	1.000	-	-		X1349
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840