Protein Alignment CaMKII and RCK2

DIOPT Version :9

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_013349.1
• Gene: RCK2 / 850950
• SGDID: S000004238
• Length: 610
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 136/481 - (28%)
• Similarity: 210/481 - (43%)
• Gaps: 135/481 - (28%)

  Fly    14 YDIKEELGKGAFSIVKRCV-QKSTGFEF--------AAKII-----------NTKKLTARDFQKL 58
            |.:..::|:||||.|.|.: .|::..||        |.|:|           :.||...:|..|.
Yeast   163 YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKT 227

  Fly    59 EREARICRK--LHH------PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASH 115
            ....::.::  ||.      ..||...|..:.::|:|::.:|:||||:|.:||...::||..:.|
Yeast   228 SSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRH 292

  Fly   116 CIQQILESVNHCHQNGVVHRDLKPENLLL-------------------ASKA-KG---------- 150
            .|:|:..:|.|.|..||||||:||||||.                   .:|| :|
Yeast   293 VIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGG 357

  Fly   151 -AAVKLADFGLAIEVQGDHQAWFGFA-------GTPGYLSPEVLKKEPYGKSVDIWACGVILYIL 207
             ..||||||||:.::         |:       ||.||.:|||:|.|.|...||:|..|.:||.:
Yeast   358 IGIVKLADFGLSKQI---------FSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTM 413

  Fly   208 LVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWI 272
            |.|:|||:||....|..:|..|.|.:..|.||.::..|||.:.::|.:.|:||....:.|..||:
Yeast   414 LCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL 478

  Fly   273 CQRERVASVVHRQETVDCLKKFNARRKLKGAIL----------------TTML------------ 309
                         .|.|||.|.....:.|....                :::|
Yeast   479 -------------NTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAF 530

  Fly   310 ----ATRNFSSRSMITKKGEGS--QVKESTDSSSTTLEDDDIKEDK-KGTVDRSTTVVSKEPEDI 367
                |.:......|.|:.|.||  :.:|..||.|....|:.::::. :.|:|.||
Yeast   531 DIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTST---------- 585

  Fly   368 RILCPAKTYQQN-IGNSQCSSAARRQ 392
             ||...|..|:| :|.:...||..|:
Yeast   586 -ILQRRKKVQENDVGPTIPISATIRE 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	111/354 (31%)
		S_TKc	14..272	CDD:214567	104/323 (32%)
		CaMKII_AD	390..517	CDD:285524	1/3 (33%)
RCK2	NP_013349.1	STKc_RCK1-like	161..478	CDD:270998	104/323 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910