DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK29

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_974150.2	Gene:	CPK29 / 843936	AraportID:	AT1G76040	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	428	Identity:	149/428 - (34%)
Similarity:	220/428 - (51%)	Gaps:	70/428 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKL-HHPNIVRL 76
            ||:.:|||:|.|.|..:|..||.|.|:|.|.|:.:||..| |.:.:.||..|.:.| ..||||..
plant   112 YDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEF 176

  Fly    77 HDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            ..:.::::..:||.:|.:|||||:.|:.:..|||.:|::..:||:..|:.||..|||||||||||
plant   177 RGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPEN 241

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            .||.|..:.:.:|..||||::.:: :.:.:....|:..|::||||.:. |||.:|:|:.||:|||
plant   242 FLLVSNEEDSPIKATDFGLSVFIE-EGKVYRDIVGSAYYVAPEVLHRN-YGKEIDVWSAGVMLYI 304

  Fly   207 LLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
            ||.|.||||.|.:..::..|..|..|..:..|.|::..||:||.:||..:|.|||||||||:|||
plant   305 LLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPW 369

  Fly   272 -----ICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKE 331
                 |..:...::|:.|      :|:|.|..|||.  |...:...|.|...:   ||.....|.
plant   370 MTDTKISDKPINSAVLVR------MKQFRAMNKLKK--LALKVIAENLSEEEI---KGLKQTFKN 423

  Fly   332 -STDSSST---------------TLEDDDIKE-------DKKGTVDRSTTVVSKEPEDIRILCPA 373
             .||.|.|               .|.:.:||:       ||.||:|....|
plant   424 MDTDESGTITFDELRNGLHRLGSKLTESEIKQLMEAADVDKSGTIDYIEFV-------------- 474

  Fly   374 KTYQQNIGNSQCSSAARRQEIIKITEQLIEAINSGDFD 411
                         :|...:..::..|.||||....|.|
plant   475 -------------TATMHRHRLEKEENLIEAFKYFDKD 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	122/295 (41%)
		S_TKc	14..272	CDD:214567	113/264 (43%)
		CaMKII_AD	390..517	CDD:285524	7/22 (32%)
CPK29	NP_974150.2	S_TKc	112..370	CDD:214567	112/259 (43%)
		STKc_CAMK	112..369	CDD:270687	111/258 (43%)
		PTZ00184	405..548	CDD:185504	26/125 (21%)
		EFh	417..476	CDD:238008	14/85 (16%)
		EFh	489..549	CDD:238008	6/11 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.970