DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK33

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001320603.1	Gene:	CPK33 / 841492	AraportID:	AT1G50700	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	160/484 - (33%)
Similarity:	244/484 - (50%)	Gaps:	63/484 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKL-TARDFQKLEREARICRKLH-HPNIVRL 76
            |.:.:|||:|.|.:...|.:||||..||.|.|:.||| |..|.:.:.||.:|.:.|. .||||..
plant    73 YTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVEF 137

  Fly    77 HDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            ..:.::|....||.:|..|||||:.|:|:..|||..|:...:||:..||.||..||:||||||||
plant   138 KGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICHFMGVMHRDLKPEN 202

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            .||:||.:.|.:|..||||::.:: :.:.:....|:..|::|||||:. |||.:|||:.|:||||
plant   203 FLLSSKDEKALIKATDFGLSVFIE-EGRVYKDIVGSAYYVAPEVLKRR-YGKEIDIWSAGIILYI 265

  Fly   207 LLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
            ||.|.||||.|.:..::..|..|..|:.|..|.:::..||:|:.:|||.:|.:||:|||.|||||
plant   266 LLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPW 330

  Fly   272 ICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSS 336
            :.:....:........:..:|:|.|..|||.  |...:...|..:..:...|...:.:  .||:|
plant   331 LREGGEASDKPIDSAVLSRMKQFRAMNKLKK--LALKVIAENIDTEEIQGLKAMFANI--DTDNS 391

  Fly   337 STTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAARRQEIIKITEQL 401
            . |:..:::||.......|.|..      :::.|..|.::.|:                ||...|
plant   392 G-TITYEELKEGLAKLGSRLTEA------EVKQLMDAVSFDQD----------------KIVHLL 433

  Fly   402 IEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLL 466
            :|.:.       |.|   .:...:.:..||  ..||:.:|            |..|:   |.|.|
plant   434 LECLK-------TPI---RVFVIQADVDGN--GSIDYIEF------------ITATM---HRHRL 471

  Fly   467 -GEEAACIAYVRLTQYIDKQGHAHTHQSE 494
             ..|....|:    |:.||.|..:....|
plant   472 ESNENVYKAF----QHFDKDGSGYITTDE 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	123/290 (42%)
		S_TKc	14..272	CDD:214567	116/259 (45%)
		CaMKII_AD	390..517	CDD:285524	23/106 (22%)
CPK33	NP_001320603.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970