DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and AT1G49580

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_175381.1	Gene:	AT1G49580 / 841382	AraportID:	AT1G49580	Length:	606	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	152/558 - (27%)
Similarity:	221/558 - (39%)	Gaps:	141/558 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQK-----STGFEFAAKII-NTKKLTARDFQKLEREARICRKL 68
            |....::.||:|:|.|...  |..|     ..|...|.||| .:|..||...:.:.||.:|.:.|
plant   146 FHSRVELGEEIGRGHFGYT--CSAKFKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREVKILQAL 208

  Fly    69 H-HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAR-EFYSEADASHCIQQILESVNHCHQNG 131
            . |.|:|:.:|:.::....|:..:|..||||.:.|:|| ..|||.||...|.|||..|..||..|
plant   209 SGHKNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCHFQG 273

  Fly   132 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVD 196
            ||||||||||.|..||.:.:.:|..||||:..|:.|.:. ....|:..|::||||.:. |....|
plant   274 VVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPDERL-NDIVGSAYYVAPEVLHRS-YTTEAD 336

  Fly   197 IWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRI 261
            :|:.|||.||||.|..|||...:..::..:......:..|.|..::.:||:.:.::|..:|.:|:
plant   337 VWSIGVIAYILLCGSRPFWARTESGIFRAVLKADPSFDEPPWPFLSSDAKDFVKRLLFKDPRRRM 401

  Fly   262 TAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEG 326
            :|::||.||||                   :.:|....:...||.         .|.|.......
plant   402 SASQALMHPWI-------------------RAYNTDMNIPFDILI---------FRQMKAYLRSS 438

  Fly   327 SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAARR 391
            |..|.:..:.|.||..|:|...|               ....:|.|.|.....:...:.:.|:..
plant   439 SLRKAALRALSKTLIKDEILYLK---------------TQFSLLAPNKDGLITMDTIRMALASNA 488

  Fly   392 QEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEAL----GNLVEGIDFHKFYFENVLGKNCK 452
            .|.:|  |..|                       ||.|    |....|:||.:|         |.
plant   489 TEAMK--ESRI-----------------------PEFLALLNGLQYRGMDFEEF---------CA 519

  Fly   453 AINTTILNPHVHLLGEEAAC------IAYVRLTQYIDKQG---------------------HAHT 490
            |    .:|.|.|   |...|      .||    :..||.|                     |:..
plant   520 A----AINVHQH---ESLDCWEQSIRHAY----ELFDKNGNRAIVIEELASELGVGPSIPVHSVL 573

  Fly   491 HQSEETRVWHKR-DNKWQNVHFHR---SASAKISGATT 524
            |.      |.:. |.|.....|.:   ..|.:.||.||
plant   574 HD------WIRHTDGKLSFFGFVKLLHGVSVRASGKTT 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	100/298 (34%)
		S_TKc	14..272	CDD:214567	97/265 (37%)
		CaMKII_AD	390..517	CDD:285524	30/161 (19%)
AT1G49580	NP_175381.1	S_TKc	151..412	CDD:214567	97/264 (37%)
		STKc_CAMK	151..411	CDD:270687	96/263 (37%)
		FRQ1	452..592	CDD:227455	38/205 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.060