DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK34

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_197437.1	Gene:	CPK34 / 832056	AraportID:	AT5G19360	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	153/462 - (33%)
Similarity:	240/462 - (51%)	Gaps:	50/462 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 NYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKLHH----PN 72
            :|.:.:|||:|.|.:...|.||:||.:||.|.|..:||..: |.:.:.||.:|   :||    ||
plant    67 SYTLGKELGRGQFGVTHLCTQKATGLQFACKTIAKRKLVNKEDIEDVRREVQI---MHHLTGQPN 128

  Fly    73 IVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDL 137
            ||.|..:.::::..:||.:|..|||||:.|:|:..|||..|:..::.|::.::.||..||:||||
plant   129 IVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIIHTCHSMGVIHRDL 193

  Fly   138 KPENLLLASKAKGAAVKLADFGLAI-----EVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDI 197
            ||||.||.||.:.:.:|..||||::     ||..|      ..|:..|::||||::: ||...||
plant   194 KPENFLLLSKDENSPLKATDFGLSVFYKPGEVFKD------IVGSAYYIAPEVLRRK-YGPEADI 251

  Fly   198 WACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRIT 262
            |:.||:|||||.|.||||.|.::.:::.|.:|..|:.|..|..::|:||:|:.:||..:|.:|:|
plant   252 WSIGVMLYILLCGVPPFWAESENGIFNAILSGQVDFSSDPWPVISPQAKDLVRKMLNSDPKQRLT 316

  Fly   263 AAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGS 327
            ||:.|.||||.:......|......:..||:|.|....|...|..:....:......:.:..:|.
plant   317 AAQVLNHPWIKEDGEAPDVPLDNAVMSRLKQFKAMNNFKKVALRVIAGCLSEEEIMGLKEMFKGM 381

  Fly   328 QVKESTDSSST-TLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAK-----TYQQNIGNSQCS 386
                .||:|.| |||     |.::|...:.|.:...|.:.:.....|.     .|.:.|..:...
plant   382 ----DTDNSGTITLE-----ELRQGLAKQGTRLSEYEVQQLMEAADADGNGTIDYGEFIAATMHI 437

  Fly   387 SAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPE-ALG--NLVEGIDFHKFYFENVLG 448
            :...|:|.:....|..:..|||           ::|..|.| ||.  .:.:|.|..:...| |.|
plant   438 NRLDREEHLYSAFQHFDKDNSG-----------YITTEELEQALREFGMNDGRDIKEIISE-VDG 490

  Fly   449 KNCKAIN 455
            .|...||
plant   491 DNDGRIN 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	118/299 (39%)
		S_TKc	14..272	CDD:214567	110/267 (41%)
		CaMKII_AD	390..517	CDD:285524	19/69 (28%)
CPK34	NP_197437.1	Pkinase	68..326	CDD:278497	110/267 (41%)
		STKc_CAMK	68..325	CDD:270687	109/266 (41%)
		PTZ00184	366..505	CDD:185504	34/153 (22%)
		EFh	374..433	CDD:238008	15/67 (22%)
		EFh	449..506	CDD:238008	17/61 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970