DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK5

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001329080.1	Gene:	CPK5 / 829685	AraportID:	AT4G35310	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	379	Identity:	131/379 - (34%)
Similarity:	201/379 - (53%)	Gaps:	40/379 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKL-HHPNIV 74
            |.|.:..:||:|.|.....|.:.::|.::|.|.|:.:||.:: |.:.:.||.:|...| .|.:||
plant    95 DIYTLSRKLGQGQFGTTYLCTEIASGVDYACKSISKRKLISKEDVEDVRREIQIMHHLAGHGSIV 159

  Fly    75 RLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKP 139
            .:..:.::..|.::|.:|..|||||:.|:.|..|||..|:...:.|:..|..||..||:||||||
plant   160 TIKGAYEDSLYVHIVMELCAGGELFDRIIQRGHYSERKAAELTKIIVGVVEACHSLGVMHRDLKP 224

  Fly   140 ENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVIL 204
            ||.||.:|....::|..||||::..: ..|.:....|:|.|::||||.|. ||...|:|..||||
plant   225 ENFLLVNKDDDFSLKAIDFGLSVFFK-PGQIFTDVVGSPYYVAPEVLLKR-YGPEADVWTAGVIL 287

  Fly   205 YILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKH 269
            ||||.|.||||.|.|..::..:..|..|:.|..|..::..||:||.:||:..|.:|:||.|.|:|
plant   288 YILLSGVPPFWAETQQGIFDAVLKGYIDFESDPWPVISDSAKDLIRRMLSSKPAERLTAHEVLRH 352

  Fly   270 PWICQ------RERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQ 328
            ||||:      |....:|:.|      ||:|:|..|||...|..:..:   .|...|....|..|
plant   353 PWICENGVAPDRALDPAVLSR------LKQFSAMNKLKKMALKVIAES---LSEEEIAGLREMFQ 408

  Fly   329 VKESTDSSS--------------TTLEDDDIKE-------DKKGTVDRSTTVVS 361
            ..::.:|.:              :||:|.:|.:       |..||:|.|..:.:
plant   409 AMDTDNSGAITFDELKAGLRKYGSTLKDTEIHDLMDAADVDNSGTIDYSEFIAA 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	116/298 (39%)
		S_TKc	14..272	CDD:214567	102/259 (39%)
		CaMKII_AD	390..517	CDD:285524
CPK5	NP_001329080.1	STKc_CAMK	97..354	CDD:270687	101/258 (39%)
CPK5	NP_001329080.1	PTZ00184	391..533	CDD:185504	14/75 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970