DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK15

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001190794.1	Gene:	CPK15 / 828283	AraportID:	AT4G21940	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	148/494 - (29%)
Similarity:	234/494 - (47%)	Gaps:	130/494 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKLH-HPNIVRL 76
            |.:.:|||:|.|.|...|.:.|||..:|.|.|..:|||.: |...::||.:|.:.|. ..|||.:
plant   102 YTLGKELGRGQFGITYTCKENSTGNTYACKSILKRKLTRKQDIDDVKREIQIMQYLSGQENIVEI 166

  Fly    77 HDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            ..:.::....:||.:|..|.|||:.|:|:..|||..|:..|:.:|..|..||..||:||||||||
plant   167 KGAYEDRQSIHLVMELCGGSELFDRIIAQGHYSEKAAAGVIRSVLNVVQICHFMGVIHRDLKPEN 231

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            .||||..:.|.:|..||||::.:: :.:.:....|:..|::||||::. |||.:|||:.|:||||
plant   232 FLLASTDENAMLKATDFGLSVFIE-EGKVYRDIVGSAYYVAPEVLRRS-YGKEIDIWSAGIILYI 294

  Fly   207 LLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
            ||.|.||||.|.:..::::|..|..|:.|..|.:::..||:|:.::||.:|.:||:||:||:|||
plant   295 LLCGVPPFWSETEKGIFNEIIKGEIDFDSQPWPSISESAKDLVRKLLTKDPKQRISAAQALEHPW 359

  Fly   272 ICQRERV-----ASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKE 331
            |...|..     ::|:.|      :|:|.|..|||...|..:
plant   360 IRGGEAPDKPIDSAVLSR------MKQFRAMNKLKKLALKVI----------------------- 395

  Fly   332 STDSSSTTLEDDDIK----------EDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQ-NIGNSQC 385
                 :.:|.:::||          .||.||:                     ||:: ..|.::.
plant   396 -----AESLSEEEIKGLKTMFANMDTDKSGTI---------------------TYEELKNGLAKL 434

  Fly   386 SSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDF-----HKFYFEN 445
            .|.....|:    :||:||   .|.||                 ...::.|:|     |::.|:.
plant   435 GSKLTEAEV----KQLMEA---ADVDG-----------------NGTIDYIEFISATMHRYRFDR 475

  Fly   446 VLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDK 484
                          :.||            .:..||.||
plant   476 --------------DEHV------------FKAFQYFDK 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	118/295 (40%)
		S_TKc	14..272	CDD:214567	107/259 (41%)
		CaMKII_AD	390..517	CDD:285524	18/100 (18%)
CPK15	NP_001190794.1	S_TKc	102..360	CDD:214567	107/259 (41%)
		STKc_CAMK	102..359	CDD:270687	106/258 (41%)
		PTZ00184	395..540	CDD:185504	29/193 (15%)
		EFh	407..466	CDD:238008	18/103 (17%)
		EFh	478..539	CDD:238008	6/23 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970