DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK21

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001319867.1	Gene:	CPK21 / 825807	AraportID:	AT4G04720	Length:	531	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	152/506 - (30%)
Similarity:	241/506 - (47%)	Gaps:	134/506 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAK-IINTKKLTARDFQKLEREARICRKLH-HPNIVRL 76
            |.:.:|||:|.|.|...|.:..||..:|.| |:..|.::.:|.:.::||.:|.:.|. .||||.:
plant    80 YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQIMQYLSGQPNIVEI 144

  Fly    77 HDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            ..:.::....:||.:|..|||||:.|:|:..|||..|:..|:.|:..|..||..|||||||||||
plant   145 KGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPEN 209

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            .||:||.:.|.:|..||||::.:: :.:.:....|:..|::||||::. |||.:|||:.||||||
plant   210 FLLSSKEENAMLKATDFGLSVFIE-EGKVYRDIVGSAYYVAPEVLRRS-YGKEIDIWSAGVILYI 272

  Fly   207 LLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
            ||.|.||||.|::..::.::..|..|:.|..|.:::..||:|:.:|||.:|.:|||||:.|:|||
plant   273 LLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAKDLVRKMLTKDPKRRITAAQVLEHPW 337

  Fly   272 ICQRERV-----ASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKE 331
            |...|..     ::|:.|      :|:|.|..|||...|..:
plant   338 IKGGEAPDKPIDSAVLSR------MKQFRAMNKLKKLALKVI----------------------- 373

  Fly   332 STDSSSTTLEDDDIK----------EDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQ-NIGNSQC 385
                 :.:|.:::||          .||.||:                     ||:: ..|.::.
plant   374 -----AESLSEEEIKGLKTMFANIDTDKSGTI---------------------TYEELKTGLTRL 412

  Fly   386 SSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEG-IDFHKFYFENVLGK 449
            .|.....|:    :||:||   .|.||                     .| ||:::|
plant   413 GSRLSETEV----KQLMEA---ADVDG---------------------NGTIDYYEF-------- 441

  Fly   450 NCKAINTTI------LNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSE 494
                |:.|:      .:.||:            :..|:.||....|..:.|
plant   442 ----ISATMHRYKLDRDEHVY------------KAFQHFDKDNSGHITRDE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	119/295 (40%)
		S_TKc	14..272	CDD:214567	108/259 (42%)
		CaMKII_AD	390..517	CDD:285524	21/112 (19%)
CPK21	NP_001319867.1	STKc_CAMK	79..337	CDD:270687	107/258 (41%)
CPK21	NP_001319867.1	PTZ00184	373..518	CDD:185504	32/205 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970