DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CaMKII and AT3G49370

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_190506.1	Gene:	AT3G49370 / 824099	AraportID:	AT3G49370	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	137/483 - (28%)
Similarity:	220/483 - (45%)	Gaps:	66/483 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQKS-----TGFEFAAKIINTKKLT-ARDFQKLEREARICRKL 68
            |...|::..|:|:|.|.  ..|..|:     .|...|.|||:..|:| |...:.:.||.::.:.|
plant   138 FEGKYELGREVGRGHFG--HTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIEDVRREVKLLKAL 200

  Fly    69 H-HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAR-EFYSEADASHCIQQILESVNHCHQNG 131
            . |.::|:.:|..::.:..::|.:|..||||.:.|:|| ..|.||:|...:.|||.:....|..|
plant   201 SGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAKRILVQILSATAFFHLQG 265

  Fly   132 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVD 196
            ||||||||||.|..||.:.|.:|:.||||:...:.| |......|:..|::||||.:. |....|
plant   266 VVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYARFD-QRLNDVVGSAYYVAPEVLHRS-YSTEAD 328

  Fly   197 IWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRI 261
            ||:.|||.||||.|..||:...:..::..:.....::....|.:::|.||:.:.::|..:..||:
plant   329 IWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFDDLPWPSISPIAKDFVKRLLNKDHRKRM 393

  Fly   262 TAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEG 326
            |||:||.|||:           |.|....|..|:..:.:|..|..:........|.|....:.|.
plant   394 TAAQALAHPWL-----------RDENPGLLLDFSIYKLVKSYIRASPFRRAALKSLSKAIPEEEL 447

  Fly   327 SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAARR 391
            ..:|    :....||    .||....:...||.:::...|..|                  .:|.
plant   448 VFLK----AQFMLLE----PEDGGLHLHNFTTALTRYATDAMI------------------ESRL 486

  Fly   392 QEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINT 456
            .:|:.:.:.|  |....||:   :.|...::.::.||   |.|........||:...:..:||:
plant   487 PDILNMMQPL--AHKKLDFE---EFCAASVSVYQLEA---LEEWEQIATVAFEHFESEGSRAIS- 542

  Fly   457 TILNPHVHLLGEEAAC--IAYVRLTQYI 482
                  |..|.||.:.  .||..|..:|
plant   543 ------VQELAEEMSLGPNAYPLLKDWI 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	100/298 (34%)
		S_TKc	14..272	CDD:214567	94/265 (35%)
		CaMKII_AD	390..517	CDD:285524	23/95 (24%)
AT3G49370	NP_190506.1	STKc_CAMK	141..403	CDD:270687	93/265 (35%)
AT3G49370	NP_190506.1	S_TKc	142..404	CDD:214567	94/265 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060