DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and PPCK2

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_566229.1	Gene:	PPCK2 / 819609	AraportID:	AT3G04530	Length:	278	Species:	Arabidopsis thaliana

Alignment Length:	275	Identity:	96/275 - (34%)
Similarity:	156/275 - (56%)	Gaps:	28/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKL-TARDFQKLEREARICRKL-HHPNIV 74
            :||.:.:|:|:|.|..:.||...:|...:|.|.|:.:.| .|.|.:.:|.|.||...| .||||:
plant     9 NNYQLCDEIGRGRFGTITRCFSPATKEFYACKTIDKRVLIDALDRECIETEPRIMAMLPPHPNII 73

  Fly    75 RLHDSIQEENYHYLVFDLV------------TGGELFEDIVAREFYSEADASHCIQQILESVNHC 127
            |:.|..:.|:...:|.:||            .||.|          ||::::...:|||.::.||
plant    74 RIFDLYETEDSLAIVMELVDPPMTIYDRLISAGGRL----------SESESASYAKQILSALAHC 128

  Fly   128 HQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYG 192
            |:..|||||:||:|:|:...:.|  |||.|||.|:.:.|:...  |..|||.|::|||:....|.
plant   129 HRCDVVHRDVKPDNVLVDLVSGG--VKLCDFGSAVWLGGETAE--GVVGTPYYVAPEVVMGRKYD 189

  Fly   193 KSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNP 257
            :.||||:.||::|.:|.|.|||..|....::..|..|...:|..::.:|:.|||:|:.:|:..:.
plant   190 EKVDIWSAGVVIYTMLAGEPPFNGETAEDIFESILRGNLRFPPKKFGSVSSEAKDLLRKMICRDV 254

  Fly   258 NKRITAAEALKHPWI 272
            ::|.:|.:||:|.|:
plant   255 SRRFSAEDALRHSWM 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	96/275 (35%)
		S_TKc	14..272	CDD:214567	94/271 (35%)
		CaMKII_AD	390..517	CDD:285524
PPCK2	NP_566229.1	STKc_CAMK	10..268	CDD:270687	95/271 (35%)
PPCK2	NP_566229.1	S_TKc	11..269	CDD:214567	94/271 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920