DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK16

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_179379.1	Gene:	CPK16 / 816299	AraportID:	AT2G17890	Length:	571	Species:	Arabidopsis thaliana

Alignment Length:	410	Identity:	124/410 - (30%)
Similarity:	210/410 - (51%)	Gaps:	52/410 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKL-HHPN 72
            |...|.|.:.||.|.|........|.||...|.|.|:..|:|.. ..:.::||.:|.:.| .|.|
plant   104 FDHRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKILQALTGHEN 168

  Fly    73 IVRLHDSIQEENYHYLVFDLVTGGELFEDIVARE--FYSEADASHCIQQILESVNHCHQNGVVHR 135
            :||.:::.:::|..|:|.:|..||||.:.|:||:  .|||.||:..::|:|:....||..|:|||
plant   169 VVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAVVVRQMLKVAAECHLRGLVHR 233

  Fly   136 DLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWAC 200
            |:||||.|..|..:.:.:|..||||:..:: ..:.:....|:..|::|||||:.. |...|:|:.
plant   234 DMKPENFLFKSTEEDSPLKATDFGLSDFIK-PGKKFHDIVGSAYYVAPEVLKRRS-GPESDVWSI 296

  Fly   201 GVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAE 265
            |||.||||.|..||||:.:..::.::.....|:....|.|::..||:.:.::|..:|..|:|||:
plant   297 GVISYILLCGRRPFWDKTEDGIFKEVLKNKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQ 361

  Fly   266 ALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVK 330
            ||.|||:.:....:.:     .:|.....|.|:.:|.:.|      :.|:.|::.|...|    :
plant   362 ALSHPWVREGGDASEI-----PIDISVLNNMRQFVKFSRL------KQFALRALATTLDE----E 411

  Fly   331 ESTDSSSTTLED--DDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAARRQE 393
            |..|     |.|  |.|..||.|.:..         |::| ...||.:...:.:::.:
plant   412 ELAD-----LRDQFDAIDVDKNGVISL---------EEMR-QALAKDHPWKLKDARVA------- 454

  Fly   394 IIKITEQLIEAINSGDFDGY 413
                  ::::||:| :.||:
plant   455 ------EILQAIDS-NTDGF 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	100/294 (34%)
		S_TKc	14..272	CDD:214567	95/261 (36%)
		CaMKII_AD	390..517	CDD:285524	5/24 (21%)
CPK16	NP_179379.1	STKc_CAMK	107..367	CDD:270687	94/261 (36%)
		S_TKc	108..368	CDD:214567	95/261 (36%)
		PTZ00184	404..549	CDD:185504	20/97 (21%)
		EFh	415..476	CDD:238008	17/82 (21%)
		EFh	496..550	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970