DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and CPK6

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001324056.1	Gene:	CPK6 / 816235	AraportID:	AT2G17290	Length:	544	Species:	Arabidopsis thaliana

Alignment Length:	443	Identity:	146/443 - (32%)
Similarity:	221/443 - (49%)	Gaps:	55/443 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKL-HHPNIV 74
            |.|.:..:||:|.|.....|...:||.::|.|.|:.:||.:: |.:.:.||.:|...| .|.|||
plant    83 DLYTLSRKLGQGQFGTTYLCTDIATGVDYACKSISKRKLISKEDVEDVRREIQIMHHLAGHKNIV 147

  Fly    75 RLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKP 139
            .:..:.::..|.::|.:|..|||||:.|:.|..|||..|:...:.|:..|..||..||:||||||
plant   148 TIKGAYEDPLYVHIVMELCAGGELFDRIIHRGHYSERKAAELTKIIVGVVEACHSLGVMHRDLKP 212

  Fly   140 ENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVIL 204
            ||.||.:|....::|..||||::..: ..|.:....|:|.|::||||.|. ||...|:|..||||
plant   213 ENFLLVNKDDDFSLKAIDFGLSVFFK-PGQIFKDVVGSPYYVAPEVLLKH-YGPEADVWTAGVIL 275

  Fly   205 YILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKH 269
            ||||.|.||||.|.|..::..:..|..|:.:..|..::..||:||.:||..:|::|:||.|.|:|
plant   276 YILLSGVPPFWAETQQGIFDAVLKGYIDFDTDPWPVISDSAKDLIRKMLCSSPSERLTAHEVLRH 340

  Fly   270 PWICQ------RERVASVVHRQETVDCLKKFNARRKLKG---------------AILTTMLATRN 313
            ||||:      |....:|:.|      ||:|:|..|||.               |.|..|....:
plant   341 PWICENGVAPDRALDPAVLSR------LKQFSAMNKLKKMALKVIAESLSEEEIAGLRAMFEAMD 399

  Fly   314 FSSRSMITKKGEGSQVKESTDSSSTTLEDDDIKE-------DKKGTVDRS----TTVVSKEPEDI 367
            ..:...||    ..::|.......:||:|.:|::       |..||:|.|    .|:...:.|..
plant   400 TDNSGAIT----FDELKAGLRRYGSTLKDTEIRDLMEAADVDNSGTIDYSEFIAATIHLNKLERE 460

  Fly   368 RILCPAKTYQQNIGNSQCSSAARRQEIIK--ITEQLIEAI-------NSGDFD 411
            ..|..|..|....|:...:....:|..|:  :|:..:|.|       |.|..|
plant   461 EHLVSAFQYFDKDGSGYITIDELQQSCIEHGMTDVFLEDIIKEVDQDNDGRID 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	117/313 (37%)
		S_TKc	14..272	CDD:214567	103/259 (40%)
		CaMKII_AD	390..517	CDD:285524	8/31 (26%)
CPK6	NP_001324056.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	227	1.000	Domainoid score	I670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.970