Protein Alignment CaMKII and camk2b2

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_009303979.1
• Gene: camk2b2 / 798222
• ZFINID: ZDB-GENE-090312-34
• Length: 537
• Species: Danio rerio
• Alignment Length: 572
• Identity: 372/572 - (65%)
• Similarity: 425/572 - (74%)
• Gaps: 100/572 - (17%)

  Fly     3 APAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRK 67
            |...||||:|.|.:.|||||||||:|:||.:.|||.|:|:||||||||:|||.|||||||||||.
Zfish     2 ATTTCTRFTDEYQLYEELGKGAFSVVRRCAKLSTGQEYASKIINTKKLSARDHQKLEREARICRL 66

  Fly    68 LHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132
            |.|.|||||||||.||.:|||:|||||||||||||||||:|||||||||||||||:|.||||.||
Zfish    67 LKHSNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131

  Fly   133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDI 197
            |||||||||||||||.|.|||||||||||||||||.||||||||||||||||||:||.|||.|||
Zfish   132 VHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDI 196

  Fly   198 WACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRIT 262
            |||||||||||||||||||||||:||.||||||||:|||||||||||||||||||||:||.||||
Zfish   197 WACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPVKRIT 261

  Fly   263 AAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------------ 315
            |.|||||||:|||..|||::||||||:||||||||||||||||||||.:||||
Zfish   262 AQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSVGRQTTAPSTIS 326

  Fly   316 ---------SRSMITKKGE-------------------GS------------------QVKESTD 334
                     ::|::.||.|                   ||                  .:|||:|
Zfish   327 AATGLVEQAAKSLLNKKTEVKPQSQSNSVKSSSVSSPKGSVPPPALEPQTTVIHNPVDGIKESSD 391

  Fly   335 SSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAARRQEIIKITE 399
            ||:||:||:|::                                          ||:||||||||
Zfish   392 SSNTTIEDEDVR------------------------------------------ARKQEIIKITE 414

  Fly   400 QLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVH 464
            ||||.:|:|||:.|.|:|||.||:||||||||||||:|||:|||||.|.||.|.|:|||||||||
Zfish   415 QLIEGLNNGDFEAYAKMCDPGLTSFEPEALGNLVEGMDFHRFYFENSLSKNSKPIHTTILNPHVH 479

  Fly   465 LLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSAS 516
            |:||:.|||||:||||::|.||...:.|||||||||:|:::|||:|||.|.:
Zfish   480 LIGEDGACIAYIRLTQFVDGQGLPRSSQSEETRVWHRRESRWQNIHFHCSGA 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	247/290 (85%)
		CaMKII_AD	390..517	CDD:285524	90/127 (71%)
camk2b2	XP_009303979.1	STKc_CaMKII	11..302	CDD:270988	247/290 (85%)
		CaMKII_AD	405..532	CDD:285524	90/127 (71%)