Protein Alignment CaMKII and camk2g2

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_005156961.1
• Gene: camk2g2 / 793359
• ZFINID: ZDB-GENE-070323-2
• Length: 626
• Species: Danio rerio
• Alignment Length: 622
• Identity: 388/622 - (62%)
• Similarity: 446/622 - (71%)
• Gaps: 108/622 - (17%)

  Fly     1 MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARIC 65
            ||....||||:|.|.:.|||||||||:|:|||:||||.|:||||||||||:|||.||||||||||
Zfish     1 MATIVTCTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARIC 65

  Fly    66 RKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130
            |.|.|||||||||||.||.:|||||||||||||||||||||:|||:||||||.||||||:|.||:
Zfish    66 RLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSESDASHCINQILESVSHIHQH 130

  Fly   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
            .:|||||||||||||||.|||||||||||||||||||.||||||||||||||||||:|:||||.|
Zfish   131 DIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195

  Fly   196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            |||||||||||||||||||||||||:||.||||||||:|||||||||||||||||||||:||.||
Zfish   196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKR 260

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS---------- 315
            |||.:||||||:|||..|||::||||||:||:|||||||||||||||||.:||||
Zfish   261 ITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQHTSPAT 325

  Fly   316 ------------SRSMITKKGEG--------------SQVKESTDSSS----------------- 337
                        .:|::.||.:|              |..|:|:.||:
Zfish   326 PTTSTAALAQEACKSLLNKKSDGVKPQTNNNKNSVVSSSTKDSSISSTAPMEPQTTVVHNPADGT 390

  Fly   338 -------TTLEDDDIKEDK--KGTVDRSTTVVSK--------------------------EPEDI 367
                   .|.|::|:|..|  .|.|...:.|||:                          .|.|:
Zfish   391 KGSTESCNTTEEEDMKGRKVSVGGVSSDSAVVSQCSGSEEPSPAPQAQTEASPPCPPASDPPHDV 455

  Fly   368 R------------------ILCPAKTYQQNIGNSQCSSAARRQEIIKITEQLIEAINSGDFDGYT 414
            :                  :..||.|...  |:|.....:|:|||||||||||||||:|||:.||
Zfish   456 KNVAWSSSGQSSCPDLEPAVPAPASTTAG--GSSVNRQQSRKQEIIKITEQLIEAINNGDFEAYT 518

  Fly   415 KICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLT 479
            :||||.||:||||||||||||:|||||||||:|.||.|.::||||||||||:||:||||||:|||
Zfish   519 RICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPVHTTILNPHVHLIGEDAACIAYIRLT 583

  Fly   480 QYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSAS 516
            ||||.||...:.|||||||||:||.||.|:|||.|.:
Zfish   584 QYIDGQGRPRSSQSEETRVWHRRDAKWLNIHFHCSGA 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	247/290 (85%)
		CaMKII_AD	390..517	CDD:285524	97/127 (76%)
camk2g2	XP_005156961.1	STKc_CaMKII	12..303	CDD:270988	247/290 (85%)
		CaMKII_AD	494..621	CDD:285524	97/127 (76%)