Protein Alignment CaMKII and camkvl

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_009295052.1
• Gene: camkvl / 553431
• ZFINID: ZDB-GENE-090311-58
• Length: 759
• Species: Danio rerio
• Alignment Length: 474
• Identity: 140/474 - (29%)
• Similarity: 233/474 - (49%)
• Gaps: 69/474 - (14%)

  Fly    11 SDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREAR----ICRKLHHP 71
            :|.|:|.:.|....|  .:.|:.|....:   |:...||...:|.:|:.:.|:    |.:.:.||
Zfish    27 TDKYEIGQVLKAKEF--CELCLVKERQTD---KVYVCKKFLKKDGRKVRKAAKNEIMILKMVKHP 86

  Fly    72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRD 136
            ||::|.|:.:.....:::.:|.|||::|:.|:.:..|:|.||::.|:|:||:|.:.|...:|||:
Zfish    87 NILQLIDAFETRKEFFIIQELATGGDVFDWILDQGNYTERDAANVIRQVLEAVAYLHSLNIVHRN 151

  Fly   137 LKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACG 201
            ||.|||:...::....|.|.||.|:   :.::.:.....|||.||:|||:.:..||:.||.||.|
Zfish   152 LKLENLMYYRESNHNKVVLRDFYLS---RFENGSITEPCGTPEYLAPEVVARHRYGRPVDCWAVG 213

  Fly   202 VILYILLVGYPPFWDE------DQHR--LYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPN 258
            ||:||||.|.|||:||      |.|.  ::.:|..|.:::.||.||.::|.||.|:.:.:.|:..
Zfish   214 VIMYILLSGNPPFYDETEEENTDMHNRIIFCRIVGGEFEFDSPYWDDISPAAKELVCRFMEVDQM 278

  Fly   259 KRITAAEALKHPWICQRERVASVVHRQETVDC--LKKFNARRKLKGAILTTMLATRNFSSRSMIT 321
            .||||.:||.|.||....  ||..:.:|.| |  .:|..|:.|.:.||..|     .|..|...|
Zfish   279 LRITAQDALTHEWIAGNG--ASEKNLKEGV-CAQFEKNFAKAKWRKAIRVT-----TFMQRLRAT 335

  Fly   322 KKG--EGSQVKESTDSSSTTLEDDDIKED----KKGTVDRSTTVVSKEPEDIRILCPAKTYQQNI 380
            ..|  :|:...::....:..|:...|:.|    ..|:|....:|.|:..|:      .:..|..:
Zfish   336 DIGSSDGAVEGQAEGVKADGLDGKGIQTDSGGVSAGSVSHEVSVESRPTEN------QEAGQTKV 394

  Fly   381 GNSQCSSAARRQEIIKITEQLIEAINSGD-FDGYTKICDPHLTA--------------------- 423
            ...:..:..:....:||  |..|.:|..: .:|.::|.|...|.
Zfish   395 EEKETETVGQSNSSLKI--QAEEPLNKKETTEGTSEIKDKPTTGANQKAASVQPIKTSDSRENSI 457

  Fly   424 -FEPEA--LGNLVEGIDFH 439
             .||||  ||::.:...||
Zfish   458 PVEPEATTLGSVEKKSPFH 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	106/304 (35%)
		CaMKII_AD	390..517	CDD:285524	17/75 (23%)
camkvl	XP_009295052.1	Protein Kinases, catalytic domain	28..292	CDD:473864	96/271 (35%)