DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CaMKII and phkg1

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001005722.1	Gene:	phkg1 / 448255	XenbaseID:	XB-GENE-987485	Length:	388	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	119/316 - (37%)
Similarity:	179/316 - (56%)	Gaps:	28/316 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINT--KKLTARDFQKLE----REARICRKL 68
            |.:.|:.||.||:|..|:|:||:.|.:..:||.|||:.  ..|::....:|.    :|..|.:|:
Frog    16 FYEKYEPKEILGRGVSSVVRRCIFKPSREDFAVKIIDITGDHLSSEQIAELRDSTVKEIDILKKV 80

  Fly    69 H-HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132
            . .||:::|.||.:...:.:|||||:..||||:.:..:...||.:....::.:||.|:..|...:
Frog    81 SGFPNVIQLKDSYESHTFFFLVFDLMRRGELFDYLTEKVTLSEKETRKIMRSLLEVVSKLHAYNI 145

  Fly   133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVL------KKEPY 191
            |||||||||:||.....   :||.|||.:.::| :.:......||||||:||:|      ....|
Frog   146 VHRDLKPENILLDDDMN---IKLTDFGFSCQIQ-EGEKLKEICGTPGYLAPEILHCSMDENHSGY 206

  Fly   192 GKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVN 256
            ||.||:|:||||:|.||.|.||||...|..:...|.:|.|.:.|||||..:...|:||.::|.||
Frog   207 GKQVDMWSCGVIMYTLLAGSPPFWHRKQMLMLRMIMSGEYHFGSPEWDDRSDTVKDLIARLLVVN 271

  Fly   257 PNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATR 312
            |.:|:||.|||.||:.           :|..|:.::.|:..||.|...||.:.:.|
Frog   272 PERRLTADEALIHPFF-----------QQYDVEEVRYFSPFRKFKVVCLTVLASVR 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	115/303 (38%)
		S_TKc	14..272	CDD:214567	109/270 (40%)
		CaMKII_AD	390..517	CDD:285524
phkg1	NP_001005722.1	PKc_like	16..290	CDD:419665	110/288 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010