DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and sqa

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	109/360 - (30%)
Similarity:	189/360 - (52%)	Gaps:	30/360 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 NYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLH 77
            :||:..|:|:|.|..|.:|..|:.|.:.|||.:...|  ..|.:.:|||..|...|.|..|::|:
  Fly    33 HYDVLGEVGRGKFGTVYKCRDKANGLQLAAKFVPIPK--REDKRNVEREVEIMNSLQHHLIIQLY 95

  Fly    78 DSIQEENYHYLVFDLVTGGELFEDIVAREF-YSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            .:.:.:....:|.:|:.|||||:.:|..|| .:|......|:|:.|::...|.||:||.||||||
  Fly    96 AAYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPEN 160

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            :|:.:: ||..:|:.|||||.:...|.:....| |||.:::|||:..:......|:|:.|||.|:
  Fly   161 ILVLTQ-KGNRIKIIDFGLARKFDPDKRLRVLF-GTPEFVAPEVVNFDCISYGTDMWSVGVICYV 223

  Fly   207 LLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
            |:.|..||..|:.....|.:....||:....::.::||..:.|.::|..:.:.|:||||.:||.|
  Fly   224 LISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKW 288

  Fly   272 ICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSS 336
            :.||...|                       |..|.:....:.:|:|.:......:...||::.|
  Fly   289 LQQRPATA-----------------------ATATPITKAASAASKSRLKSVSPVTAPSESSEDS 330

  Fly   337 STTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILC 371
            :.|:||:|  ::::..|.::.....::.|::..||
  Fly   331 TETIEDED--DEEEVAVQQAKQKDQQQDEELANLC 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	94/290 (32%)
		S_TKc	14..272	CDD:214567	90/258 (35%)
		CaMKII_AD	390..517	CDD:285524
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	90/258 (35%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	87/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010