DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and camk1ga

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_956260.1	Gene:	camk1ga / 335654	ZFINID:	ZDB-GENE-030131-7594	Length:	426	Species:	Danio rerio

Alignment Length:	308	Identity:	128/308 - (41%)
Similarity:	185/308 - (60%)	Gaps:	20/308 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CT------RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARIC 65
            ||      ...:.:|.||.||.|:||.|....::.:|..:|.|.:..|:|   ....||.|.::.
Zfish     8 CTWKKSTNNIKEIFDFKEVLGSGSFSEVYLVRERKSGNFYALKCVKKKQL---HHSNLENEIQVL 69

  Fly    66 RKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130
            :::.|.|:|.|.|..:...::|||.:||:|||||:.|:.|..|:|.|||..|.|:||:|::.|||
Zfish    70 KRIKHSNVVGLEDFYESRTHYYLVMELVSGGELFDRILDRGVYTEKDASRVINQVLEAVSYLHQN 134

  Fly   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
            .:|||||||||||..|..:.|.:.::||||:  ...||.......|||||::||||.::||.|:|
Zfish   135 SIVHRDLKPENLLYYSPDENAKIMISDFGLS--KMSDHGVMSTACGTPGYVAPEVLAQKPYSKAV 197

  Fly   196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            |.|:.|||.||||.|||||::|::.||:|:|....|.:.||.||.::..||:.|..||..||:||
Zfish   198 DCWSIGVITYILLSGYPPFYEENETRLFSKIMKAEYAFHSPYWDDISESAKDFIRHMLEKNPSKR 262

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETV----DCLKKFNARRKLKGAI 304
            .|..:||.||||     :....|....:    :.::|..|:.|.|.||
Zfish   263 YTTEQALSHPWI-----IGDTAHNDNIIHSVCEQIQKNFAKSKWKRAI 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	124/294 (42%)
		S_TKc	14..272	CDD:214567	117/257 (46%)
		CaMKII_AD	390..517	CDD:285524
camk1ga	NP_956260.1	STKc_CaMKI_gamma	17..300	CDD:271068	122/292 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920