DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and PhKgamma

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	116/283 - (40%)
Similarity:	162/283 - (57%)	Gaps:	18/283 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIIN----TKKLTARDFQKLE---REAR 63
            |...|...|:.||.||:|..|.|:||::|.||.|||||||:    |:......:..||   :|..
  Fly    15 AAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEIS 79

  Fly    64 ICRK-LHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHC 127
            |.|: :.||.|:.|.|..:.:.:.:|||:|...||||:.:.:....||......::||.|.|.:.
  Fly    80 ILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYI 144

  Fly   128 HQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLK----- 187
            |...:|||||||||:||.....   ||:.|||.|.::| :.:......||||||:||.||
  Fly   145 HAKSIVHRDLKPENILLDENHN---VKITDFGFAKQLQ-EGEKLTNLCGTPGYLAPETLKCNMFE 205

  Fly   188 -KEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQ 251
             ...|.:.|||||||||::.||||.||||...|..:...|..|.|.:.||||..::.:.|:||.:
  Fly   206 GSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRK 270

  Fly   252 MLTVNPNKRITAAEALKHPWICQ 274
            .|.|:|::|||..|.|:||:..|
  Fly   271 CLVVDPSQRITVKEVLRHPFFNQ 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	114/277 (41%)
		S_TKc	14..272	CDD:214567	113/271 (42%)
		CaMKII_AD	390..517	CDD:285524
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	114/275 (41%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	113/271 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.850