Protein Alignment CaMKII and Dclk3

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001178729.1
• Gene: Dclk3 / 316023
• RGDID: 1309232
• Length: 807
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 116/291 - (39%)
• Similarity: 177/291 - (60%)
• Gaps: 8/291 - (2%)

  Fly    13 NYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLH 77
            :|||...:|.|.|:|||.|..:.|...:|.|||:..:|..:: ..::.|..|.:.|.|||||:||
  Rat   514 HYDIGRVIGDGNFAIVKECKHRETRQAYAMKIIDKSQLKGKE-DIVDSEILIIQSLSHPNIVKLH 577

  Fly    78 DSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENL 142
            :..:.|...||:.:.|.||:||:.|:....:.|.||:..|..:.:::.|.|...:||||||||||
  Rat   578 EVYETEAEIYLIMEYVQGGDLFDAIIESVKFPEPDAAVMITDLCKALVHMHDKKIVHRDLKPENL 642

  Fly   143 LL-ASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYI 206
            |: .::.|...:||||||||..|.   :..|...|||.|::||:|.::.||..||:||.||||||
  Rat   643 LVQRNEDKSTTLKLADFGLAKHVV---RPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYI 704

  Fly   207 LLVGYPPFW--DEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKH 269
            ||.|:|||.  :.||..|::.|:.|.:::.||.||.::..||:|:..:|.|:|.||.||.:.|.|
  Rat   705 LLCGFPPFRSPERDQDELFNIIQLGQFEFLSPYWDNISDAAKDLVRNLLVVDPKKRYTAHQVLHH 769

  Fly   270 PWICQRERVASV-VHRQETVDCLKKFNARRK 299
            |||......::| ..::|:.....:|.::.|
  Rat   770 PWIGMVGHPSTVNPQKEESPSSEGRFQSQHK 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	116/291 (40%)
		CaMKII_AD	390..517	CDD:285524
Dclk3	NP_001178729.1	DCX_DCLK3	95..179	CDD:340528
		Protein Kinases, catalytic domain	514..771	CDD:473864	109/260 (42%)