Protein Alignment CaMKII and chkr-2

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_508060.1
• Gene: chkr-2 / 191613
• WormBaseID: WBGene00011612
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 339
• Identity: 107/339 - (31%)
• Similarity: 162/339 - (47%)
• Gaps: 48/339 - (14%)

  Fly     1 MAAPA----ACTRFSDNYDIKE----------ELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLT 51
            :|.||    ...|..||:..:|          .||||.|..|....:||.....|.|.:||:..|
 Worm   142 IAIPALIIFVYERADDNHHPEELTNKYHVTSHLLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFST 206

  Fly    52 --------ARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREF- 107
                    .||.|   .|..:.:||.|||||.::|.|....|.|:|.:.|.|||.|..:|..::
 Worm   207 RCSRAIAKTRDIQ---NEVEVMKKLSHPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYN 268

  Fly   108 ---YSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLA---IEVQG 166
               ..|:...:...|::::|.:.|..|:.|||:||||:|.::||:...:||.|||:|   :....
 Worm   269 QMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMAKNSVNRMK 333

  Fly   167 DHQAWFGFAGTPGYLSPEVLKKE--PYGKSVDIWACGVILYILLVGYPPFWDE-DQHRLYSQIKA 228
            .|      .|||.|.:||::..:  .|...||||:.|.:|:|...|||||.:| ...::..|:..
 Worm   334 TH------CGTPSYCAPEIVANQGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLT 392

  Fly   229 GAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKK 293
            |...: ..:|..:|.|.:|:|..||||.|..|.:|.|.:...|:    :.|..:..::  |.||.
 Worm   393 GRLFF-HEQWHRITDETQNMIQWMLTVEPLIRPSAVELMSTQWM----KCADCLSAKQ--DILKS 450

  Fly   294 FNARRKLKGAILTT 307
            .........|:.||
 Worm   451 IQPISAAPAALQTT 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	100/318 (31%)
		CaMKII_AD	390..517	CDD:285524
chkr-2	NP_508060.1	FHA_CHK2	45..153	CDD:438718	3/10 (30%)
		Protein Kinases, catalytic domain	161..435	CDD:473864	93/283 (33%)