Protein Alignment CaMKII and mnk-1

DIOPT Version :9

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_871924.2
• Gene: mnk-1 / 174623
• WormBaseID: WBGene00011304
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 138/556 - (24%)
• Similarity: 245/556 - (44%)
• Gaps: 115/556 - (20%)

  Fly    10 FSDNYDIKEE-LGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARI---CRKLHH 70
            |.|.|.:.:| ||.||:..|..|....:|.|:|.||:: |:......:::.||..|   |:  .|
 Worm   198 FFDYYKLTDEHLGSGAYGSVTTCKSIKSGVEYAVKIVD-KQGETHSRKRILREVNIFKTCK--DH 259

  Fly    71 PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHR 135
            ||||:|.|..::|...|||.:.:.||.|.:.|:.|::::|.:|....:.|..::...|..|:.||
 Worm   260 PNIVQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTEEEARRVTKDISLALKFMHDRGIAHR 324

  Fly   136 DLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-----------WFGFAGTPGYLSPEV---- 185
            |:||||:|.......:.|||.|..||.:....|:.           .....|:..:::|||
 Worm   325 DVKPENVLCTDPNHVSPVKLCDLDLASQRPPQHERHPLSQVASEPDLASPVGSAEFMAPEVVDAY 389

  Fly   186 ----LKKEPYGKSVDIWACGVILYILLVGYPPF----------WDED------QHRLYSQIKAGA 230
                ||   |.|..|.|:.||||||:|.||.||          |.|.      |..|:.:|:.|.
 Worm   390 VGDSLK---YDKKCDTWSLGVILYIMLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFHRIQDGY 451

  Fly   231 YDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQR------ERVASVVHRQETVD 289
            |::|..||..::.|||:|::.:|..:|..|..|.:.|.|.|:.|.      :..:::::|:::..
 Worm   452 YEFPEEEWGMISEEAKDLVSNLLKRDPVDRFNADQILSHRWLQQSAASTILQTPSNLINRKDSAR 516

  Fly   290 CLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSSSTTLEDD----DIKEDKK 350
            .:::.:....|...:..|.|:.| |.::..:::.|        :|..:.|:..|    .:..:..
 Worm   517 DVQQMSEHFNLMNRLADTRLSAR-FDNKMTMSECG--------SDLGTATIHGDGSFLSMGGEPF 572

  Fly   351 GTVDRSTTV---VSKEPEDIRILCPAKTYQQNIGNSQCSSAARRQEIIKITEQLIE-------AI 405
            ||..|..:|   :.|          :::.:.....|:.|.......::.::|.|.:       |.
 Worm   573 GTFPRKKSVGIAIEK----------SRSGEFTPPISRASPTTPPPSMLNLSEDLTDSPVKRRSAD 627

  Fly   406 NSGDF--------DGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPH 462
            :||.|        :|...||.|.:...:..::.....|                 |:.|::....
 Worm   628 DSGTFSLFSPASSNGDDSICSPPMVFVDMPSIQLFGTG-----------------ALLTSVQMTP 675

  Fly   463 VHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRV 498
            .|...::|:      |..:.|:|.:|:.....||:|
 Worm   676 RHTTEDDAS------LKSFEDEQENANPIHRIETQV 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	100/335 (30%)
		S_TKc	14..272	CDD:214567	95/296 (32%)
		CaMKII_AD	390..517	CDD:285524	22/124 (18%)
mnk-1	NP_871924.2	PKc_like	200..492	CDD:328722	96/297 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010