Protein Alignment CaMKII and Camk2g

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001424776.1
• Gene: Camk2g / 171140
• RGDID: 621802
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 388/586 - (66%)
• Similarity: 442/586 - (75%)
• Gaps: 74/586 - (12%)

  Fly     1 MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARIC 65
            ||..|.||||:|:|.:.|||||||||:|:|||:|::..|:||||||||||:|||.||||||||||
  Rat     1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARIC 65

  Fly    66 RKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130
            |.|.|||||||||||.||.:|||||||||||||||||||||:||||||||||.||||||||.||:
  Rat    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130

  Fly   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
            .:|||||||||||||||.||||||||||||||||||:.||||||||||||||||||:|:||||.|
  Rat   131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195

  Fly   196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            |||||||||||||||||||||||||:||.||||||||:|||||||||||||||||||||:||.||
  Rat   196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKR 260

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS---------- 315
            |||.:||||||:|||..|||::||||||:||:|||||||||||||||||.:||||
  Rat   261 ITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPAS 325

  Fly   316 ------------SRSMITKKGEG------------------------------------------ 326
                        ::|::.||.:|
  Rat   326 PAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLMPQSNNKNSLVSPAQEPAPLQTAMEPQTT 390

  Fly   327 ------SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQC 385
                  ..:|.||:|.:||.||:|:|.....|.:.|.....:.|.|  ...|:...|..  .|.|
  Rat   391 VVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRD--RTAPSAGMQPQ--PSLC 451

  Fly   386 SSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKN 450
            |||.|:|||||||||||||||:|||:.|||||||.||:||||||||||||:|||||||||:|.||
  Rat   452 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKN 516

  Fly   451 CKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSA 515
            .|.|:|||||||||::||:||||||:|||||||.||...|.|||||||||:||.||.|||:|.|.
  Rat   517 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSG 581

  Fly   516 S 516
            :
  Rat   582 A 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	245/290 (84%)
		CaMKII_AD	390..517	CDD:285524	99/127 (78%)
Camk2g	NP_001424776.1	None