Protein Alignment CaMKII and DCX

DIOPT Version :9

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_000546.2
• Gene: DCX / 1641
• HGNCID: 2714
• Length: 441
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 54/318 - (16%)
• Similarity: 114/318 - (35%)
• Gaps: 79/318 - (24%)

  Fly   112 DASHCIQQILESVNHCHQNGVV------HRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA 170
            |.|||     :|:.. |||..:      .||....|:      :|:.:.    ||.......|.:
Human    69 DRSHC-----QSLRF-HQNMELDFGHFDERDKTSRNM------RGSRMN----GLPSPTHSAHCS 117

  Fly   171 WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPS 235
            ::.........:.:..||..:.::.|.:..|::..:         ..|:.|.:..:.|   |...
Human   118 FYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAV---------SSDRFRSFDALLA---DLTR 170

  Fly   236 PEWDTVT-PEAKNLINQMLTVNPNKRITAAEALK--HPWICQRERVASVVHRQETVDCLKKFNAR 297
            ...|.:. |:.   :..:.|::.:::|.:.:.|:  ..::|..:...      :.|:..|..|..
Human   171 SLSDNINLPQG---VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFF------KKVEYTKNVNPN 226

  Fly   298 RKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSK 362
            ..:.......|.|.::.:|                 .:|:...|:.|....|..|:.||..   |
Human   227 WSVNVKTSANMKAPQSLAS-----------------SNSAQARENKDFVRPKLVTIIRSGV---K 271

  Fly   363 EPEDIRILCPAKT---YQQNIGNSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKIC 417
            ..:.:|:|...||   ::|.:.:.        .|.||:...:::.:.:  .||....|
Human   272 PRKAVRVLLNKKTAHSFEQVLTDI--------TEAIKLETGVVKKLYT--LDGKQVTC 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	32/199 (16%)
		S_TKc	14..272	CDD:214567	28/168 (17%)
		CaMKII_AD	390..517	CDD:285524	6/28 (21%)
DCX	NP_000546.2	DCX	129..219	CDD:214711	15/110 (14%)
		DCX	256..344	CDD:214711	17/77 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920