DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and Dcx

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001103692.1	Gene:	Dcx / 13193	MGIID:	1277171	Length:	366	Species:	Mus musculus

Alignment Length:	237	Identity:	39/237 - (16%)
Similarity:	87/237 - (36%)	Gaps:	57/237 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 KKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVT-PEAKNLIN 250
            ||..:.::.|.:..|::..:         ..|:.|.:..:.|   |......|.:. |:.   :.
Mouse    53 KKVRFYRNGDRYFKGIVYAV---------SSDRFRSFDALLA---DLTRSLSDNINLPQG---VR 102

  Fly   251 QMLTVNPNKRITAAEALK--HPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRN 313
            .:.|::.:::|.:.:.|:  ..::|..:...      :.|:..|..|....:.......|.|.::
Mouse   103 YIYTIDGSRKIGSMDELEEGESYVCSSDNFF------KKVEYTKNVNPNWSVNVKTSANMKAPQS 161

  Fly   314 FSSRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKT--- 375
            .:|                 .:|:...|:.|....|..|:.||..   |..:.:|:|...||
Mouse   162 LAS-----------------SNSAQARENKDFVRPKLVTIIRSGV---KPRKAVRVLLNKKTAHS 206

  Fly   376 YQQNIGNSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKIC 417
            ::|.:.:.        .|.||:...:::.:.:  .||....|
Mouse   207 FEQVLTDI--------TEAIKLETGVVKKLYT--LDGKQVTC 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	17/118 (14%)
		S_TKc	14..272	CDD:214567	13/87 (15%)
		CaMKII_AD	390..517	CDD:285524	6/28 (21%)
Dcx	NP_001103692.1	DCX1_DCX	51..139	CDD:340529	15/106 (14%)
		DCX2	176..259	CDD:340589	16/76 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..366
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920