Protein Alignment CaMKII and CaMKII

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_311134.3
• Gene: CaMKII / 1272250
• VectorBaseID: AGAMI1_012406
• Length: 490
• Species: Anopheles gambiae
• Alignment Length: 532
• Identity: 439/532 - (82%)
• Similarity: 464/532 - (87%)
• Gaps: 43/532 - (8%)

  Fly     1 MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARIC 65
            |||..|||||||||::|||||||||||||||||||||||||||||||||||:|||||||||||||
Mosquito     1 MAAQPACTRFSDNYELKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTSRDFQKLEREARIC 65

  Fly    66 RKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130
            |||.|||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
Mosquito    66 RKLQHPNIVRLHDSIQEENFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130

  Fly   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
            |||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||:|
Mosquito   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKAV 195

  Fly   196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            ||||||||||||||||||||||||||||.|||||.||||||||||||||||:||||||||||.||
Mosquito   196 DIWACGVILYILLVGYPPFWDEDQHRLYVQIKAGTYDYPSPEWDTVTPEAKSLINQMLTVNPYKR 260

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGE 325
            |:||:|||||||||||||||||||||||||||||||||||||||||||||||||||:|||.|||:
Mosquito   261 ISAADALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSKSMIAKKGD 325

  Fly   326 GSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSAAR 390
            ||||||||||||||:||||.|                                          ||
Mosquito   326 GSQVKESTDSSSTTVEDDDCK------------------------------------------AR 348

  Fly   391 RQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAIN 455
            ||||||||||||||||:||::.||||||||||:|||||||||:||:|||||.|||||||:.||||
Mosquito   349 RQEIIKITEQLIEAINNGDYETYTKICDPHLTSFEPEALGNLIEGMDFHKFNFENVLGKSNKAIN 413

  Fly   456 TTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASAKIS 520
            |||||||||:.||:.|||||||||||||||||.||.|:||||||||:||||||||||.|.:...|
Mosquito   414 TTILNPHVHIFGEDTACIAYVRLTQYIDKQGHPHTVQTEETRVWHKKDNKWQNVHFHGSRNGSFS 478

  Fly   521 G-ATTFDFIPQK 531
            . ||.:||:..|
Mosquito   479 NTATQYDFVNHK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	277/290 (96%)
		CaMKII_AD	390..517	CDD:285524	106/126 (84%)
CaMKII	XP_311134.3	STKc_CaMKII	12..303	CDD:270988	277/290 (96%)
		CaMKII_AD	348..472	CDD:285524	68/123 (55%)